Cases reported "Odontogenic Tumors"

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1/206. Cemento-ossifying fibroma presenting as a mass of the parapharyngeal and masticator space.

    We report a case of cemento-ossifying fibroma that presented as a large extraosseous mass in the masticator and parapharyngeal space. CT scanning and MR imaging showed a large extraosseous mass with central conglomerated, well-matured ossified nodules and fatty marrow. The central matured ossified nodules were of low density on CT scans and high signal intensity on T1- and T2-weighted MR images. Multiplanar reformatted CT scans revealed the origin of the mass to be at the extraction site of the right lower second molar tooth.
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ranking = 1
keywords = lower
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2/206. Clear cell odontogenic tumor in the mandible: report of a case with duct-like appearances and dentinoid induction.

    A case of clear-cell odontogenic tumor with unusual histological features is presented. A 61-year-old Japanese man was admitted because of swelling of the left premolar-molar region of the mandible. Radiological examination revealed a multilocular radiolucency with irregular margins. Histological examination of the resected specimen showed infiltrative proliferation of both clear and eosinophilic cells into the adjacent soft tissue without encapsulation, suggesting the malignant potential of the tumor. The tumor cells sporadically formed cystic lesions. In addition, several tumor cell nests showed duct-like characteristics, and many eosinophilic dentin-like structures were attached to the tumor cell nests, suggesting the potential for epithelial-mesenchymal induction. Histochemically, the clear tumor cells possessed cytoplasmic glycogen granules. Both clear and eosinophilic tumor cells showed positive immunoreactivities for cytokeratin 19, epithelial membrane antigen and filaggrin, indicating an odontogenic epithelial origin.
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ranking = 62105.743724282
keywords = mandible
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3/206. Ameloblastic fibroma: report of case.

    A 3-year-old girl had a large, painless, radiolucent lesion that involved the right side of the mandible. The lesion extended from the canine region to the condyle and coronoid process. A microscopic diagnosis of ameloblastoma was made by the hospital pathologist. Because it is unusual to find an ameloblastoma in a 3-year-old child and because the extensive surgical procedure that would be necessary to remove an ameloblastoma of this size, further consultation was required. As a result, the lesion was diagnosed as an ameloblastic fibroma and a more conservative surgical procedure was performed. Sixteen months after surgery, radiographic evidence showed complete resolution of the bony surgical defect, with no evidence of recurrence. This case once again points out the necessity for exact diagnosis of similar histologic lesions that may require a different approach in treatment.
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ranking = 12421.148744856
keywords = mandible
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4/206. Value of computed tomography and magnetic resonance imaging in the treatment of a calcifying epithelial odontogenic (Pindborg) tumour.

    The calcifying epithelial odontogenic (Pindborg) tumour is a rare primary tumour of the jaw with a characteristic histological appearance. We describe here its appearance on computed tomography (an expanding, multilocular lesion that is thinning both plates of the mandible, is well-defined and contains scattered radio-opaque areas) and magnetic resonance imaging (predominantly hypointense on T1-weighted images and of mixed hyperintensity on T2-weighted images; the extent of the tumour including involvement of the mandibular canal was clear).
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ranking = 13422.963176426
keywords = mandible, jaw
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5/206. Odontogenic ghost cell carcinoma: a case report with reference to the relation between apoptosis and ghost cells.

    The neoplastic variant of calcifying odontogenic cyst has various designations, and its malignant counterpart has been reported as aggressive epithelial odontogenic ghost cell tumor or odontogenic ghost cell carcinoma. We present a case of odontogenic ghost cell carcinoma with reference to the relation between the ghost cells and apoptosis. A 33-year-old man complained of a mandibular mass. The mass occupied the entire right side of the mandible with destruction of both buccal and lingual bone. The mass also infiltrated into submandibular and sublingual spaces. Histologically, the mass was composed of a solid proliferation of hyperchromatic and pleomorphic epithelial cells with abnormal mitoses. islands of ghost cells were frequently admixed with nucleated cells, and there were foci of ameloblastic differentiation. Immunohistochemical stains for cytokeratins, involucrin, and apoptosis-related proteins such as Bcl-2, Bcl-X(L), and Bax were done. Terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick-end labeling (TUNEL) assay was also performed. The nucleated cells adjacent to the ghost cells expressed cytokeratins and involucrin, but the ghost cells had no reaction. Bcl-2 was negative. Both Bcl-X(L) and Bax were demonstrated in the nucleated cells adjacent to the ghost cells. The ghost cells exhibited Bax protein. Some nucleated cells adjacent to the ghost cells were positive with TUNEL assay. The above results indicate that ghost cells undergo abnormal terminal differentiation as an apoptotic process.
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ranking = 12421.148744856
keywords = mandible
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6/206. Calcifying epithelial odontogenic tumor with intracranial extension: report of a case and review of the literature.

    The calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasm, possibly of stratum intermedium origin and occurring predominantly in the mandible of adults. The treatment varies, depending on its size, location, and histology. A case of an advanced CEOT arising in the maxilla with intracranial extension is reported. The report is supplemented by a review of the literature.
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ranking = 12421.148744856
keywords = mandible
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7/206. Ameloblastic carcinoma ex ameloblastoma of the mandible with malignancy-associated hypercalcemia.

    ameloblastoma is a rare, locally destructive, benign neoplasm of the jawbones, which arises from epithelium derived from the epithelial components of the developing tooth. Ameloblastic carcinoma is the term used to designate any ameloblastoma in which there is histologic evidence of malignancy in the primary tumor, regardless of whether it has metastasized. Most ameloblastic carcinomas are presumed to have arisen de novo, with few cases of malignant transformation of ameloblastoma being apparent. hypercalcemia is the most common metabolic complication of malignancy. Although malignancy-associated hypercalcemia is often reported in association with other malignancies, it is exceedingly unusual in association with ameloblastoma, malignant ameloblastoma, or ameloblastic carcinoma. We describe a patient with multiple recurrences of ameloblastoma, with subsequent malignant transformation presenting with malignancy-associated hypercalcemia.
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ranking = 50686.409410995
keywords = mandible, jaw
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8/206. Aggressive epithelial odontogenic ghost cell tumor in the mandible: CT and MR imaging findings.

    We report a case of aggressive epithelial odontogenic ghost cell tumor arising from the mandible in a 32-year-old man. On CT and MR studies, the tumor was seen as a large, heterogeneous soft-tissue mass that caused marked destruction of the mandible and invaded the mouth floor and tongue base. The tumor displayed a variety of densities and signal intensities on CT and MR images, which correlated well with the degree of cellularity of epithelial islands, abundance of ghost cells and eosinophilic materials, calcification, and cystic areas on histologic sections. Owing to the unpredictable biological behavior of this type of tumor, careful, long-term follow-up is highly recommended.
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ranking = 74526.892469138
keywords = mandible
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9/206. Developing cementoblastoma: case report and update of differential diagnosis.

    The benign cementoblastoma is a rare odontogenic tumor that tends to occur in the jaws of young people. It is most commonly characterized as a circumscribed radiopaque mass attached to the tooth roots and rimmed by a thin radiolucent zone. Early lesions, however, are radiolucent and can be confused with periapical conditions resulting from nonvital teeth. The tumor is seldom recognized until it produces pain or expansion of the jaw. If the diagnosis is established early, the tooth can be saved by endodontic treatment followed by apical root resection and surgical enucleation of the tumor. This case report documents the origin, development, and unlimited growth potential of a cementoblastoma. Radiographs taken at yearly intervals reveal an initial widening of the periodontal ligament space that grew into a 3-cm mixed radiolucent and radiopaque tumor over a 4-year period. The differential diagnosis and some criteria to help distinguish the cementoblastoma from similar-appearing lesions are reviewed.
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ranking = 2003.6288631394
keywords = jaw
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10/206. An unusual bilateral pathological fracture.

    An unusual case of a bilateral pathological fracture of the mandible has been presented. The fracture of the right side of the mandible was through an area of bacteroides osteomyelitis and the fracture of the left side of the mandible was through a large cementifying fibroma, which had replaced the left body of the mandible.
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ranking = 49684.594979425
keywords = mandible
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