1/4. dermatofibrosarcoma protuberans of the scalp.dermatofibrosarcoma protuberans is an uncommon tumour of the dermis and rarely occurs on the scalp; there are few known predisposing factors. A case is described of such a tumour that occurred at the site of radiotherapy for a basal cell carcinoma. Histological characteristics, behaviour and management of dermatofibrosarcoma protuberans are discussed.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
2/4. A case of inverted papilloma of the ureter: is the dna ploidy pattern associated with occurrence of transitional cell carcinoma of the bladder?We describe herein a case of inverted papilloma of the ureter, in which transitional cell carcinoma of the bladder developed twenty-three months after nephroureterectomy. Flow cytometric analysis of formalin-fixed and paraffin-embedded archival material of the inverted papilloma revealed dna aneuploidy pattern and relatively high percentage of s phase. Retrospectively, dna measurement thus provided the predictive value regarding biological activity and the clinical behaviour of the present case.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
3/4. Aggressive cutaneous squamous cell carcinoma of the head and neck in patients with chronic lymphocytic leukaemia.We describe multiple cutaneous squamous cell carcinomas of the head and neck in five patients with chronic lymphocytic leukaemia (CLL). When associated with CLL, cutaneous squamous cell carcinomata behave in a much more aggressive manner than otherwise expected. Four patients developed local recurrence after primary treatment. All five patients developed lymph node metastases containing squamous cell carcinoma. Three of five patients (60 per cent) had multiple primary lesions. Whereas the increased incidence of second cancers in CLL and notably of skin cancers is documented, little has been written to describe the aggressive behaviour of these tumours. It is important, when treating these patients, to be aware of the high tendency towards local recurrence and lymph node metastasis and to consider an aggressive management plan and careful follow-up.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
4/4. Cystosarcoma phylloides: heterogeneity in a rare tumour type.Mammary cystosarcoma phylloides is a rare tumour, and clear guidelines for its clinical management are lacking. We present three cases from the Western Infirmary which illustrate the range of behaviour that these tumours can manifest, and discuss some of the clinical problems that they present.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |