1/3. Solitary fibrous tumour of the thyroid gland.Solitary fibrous tumours of the thyroid gland are rare; only five cases have been reported in the literature. Clinically, they present as a long-standing firm mass in the thyroid. Histologically, they show a range of appearances including so-called 'patternless growth pattern', spindle-cell morphology, alternating hypo- and hyper-cellular areas, keloid-like hyalinization and a prominent haemangiopericytoma - like architecture. The behaviour of extrathoracic solitary fibrous tumours is unpredictable and requires careful, long-term follow-up.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
2/3. Solitary fibrous tumour in the deep soft tissue of the neck in a Chinese man.Originally described in the pleura, solitary fibrous tumour (SFT) is now reported in a variety of extrapleural sites. However, description of SFT in the deep soft tissue of the neck is very rare. In this report, we document the neoplasm, deep to the right platsyma muscle but superficial to the deep fascia just above the clavicle, in an otherwise well 50-year-old Chinese man. Histological examination of the excised specimen disclosed spindle-shaped cells disposed in short fascicles as well as randomly in association with areas of varying cellularity, keloidal hyalinisation of the stroma and haemangiopericytoma-like vessels. The tumour cells were CD34-, bcl-2- and CD99-positive. Since histological features may not accurately predict the biological behaviour of this tumour, careful long-term follow-up is advocated.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
3/3. recurrence and malignant transformation in solitary fibrous tumour of the pleura.Solitary fibrous tumours of the pleura are mesenchymal neoplasms and recurrence with malignant progression after complete resection rarely occurs. In the case of a 76-year-old patient we found multifocal recurrence with malignant transformation within six months following primary excision. Even though the vast majority of these tumours are benign, complete resection as well as clinical and radiological follow-up are highly recommended because of the potentially adverse biological behaviour and the lack of radical treatment options other than surgery.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |