Cases reported "Nasopharyngeal Diseases"

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1/3. Upper aerodigestive tract manifestations of cicatricial pemphigoid.

    Cicatricial pemphigoid is a chronic mucosal blistering disorder with a predilection for subsequent scar formation. Many physicians may be unaware of the various presentations and sequelae of this uncommon disease. This report of the largest series to date focuses on the upper aerodigestive tract manifestations of this disease. During the years 1975 to 1985, 142 patients with cicatricial pemphigoid were seen at the Mayo Clinic. There were 93 women and 49 men; the age range was 21 to 92 years. Mucosal lesions occurred most often in the mucous membranes of the oral cavity and conjunctiva. Involvement of the pharynx, larynx, and esophagus was less common. Stenosis of the nasopharynx or larynx necessitated surgical repair in several persons and caused obstructive sleep apnea in two. The otolaryngologist can make an important contribution to the early recognition, diagnosis, and management of the complications of cicatricial pemphigoid.
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2/3. Nasopharyngeal obstruction in infectious mononucleosis.

    Obstruction of the upper respiratory tract is an alarming and serious manifestation of infectious mononucleosis. The physician must distinguish this disease from other causes of upper airway obstruction. The presence of nasal obstruction by viscous secretions can aid in establishing the diagnosis of infectious mononucleosis. Steroid therapy should be initiated as soon as respiratory obstruction is apparent and infectious mononucleosis is suspected.
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3/3. craniopharyngioma with erosion and drainage into the nasopharynx. An autobiographical case report.

    This physician had a craniopharyngioma which was treated by radiation therapy in 1938, with relief of headaches and return to professional activity. Later, penetration of the tumor through the sphenoid sinus into the nasopharynx resulted in the intermittent drainage over 30 years of cystic parts of the tumor into the nasopharynx and from there to the oropharynx without any meningeal rupture. radiation therapy was the initial mode of treatment, later combined with steroid and thyroid replacement therapy. A professional career was possible in spite of the patient's health problems.
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