1/6. brain abscess by mycotic and bacterial infection in a diabetic patient: clinical report and review of literature.This report presents a case of lethal invasive mucormycosis, a rare fungal infection, which predominantly affects immunocompromised patients, and is reported in a 57-year-old female who presented with cerebral abscess. The patient, who had undiagnosed diabetes mellitus, presented with extensive right hemifacial deficiency of the bones and soft tissues consequent to surgical resection of the ethmoid-spheno-maxillo-orbital district after mucormycosis. A reconstruction with a pectoral pedunculated flap was performed. The maxillary swelling extended to the contiguous area, involving the palate and homolateral orbital floor. Mucous and cutaneous samples showed the presence of aspergillus fumigatus, and diagnosis of rhinocerebral mucormycosis was made. The patients also presented with a right hemiplegia consequent to a cerebral abscess by eikenella corrodens. The authors decided to position an intraoral prosthesis to restore palatal integrity and masticatory function and inserted four titanium fixtures for the retention of the bone-anchored facial prosthesis.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
2/6. Cutaneous zygomycosis in a diabetic HTLV-I-seropositive man.zygomycosis, an invasive fungal infection, is usually seen in persons with diabetes, particularly in those with diabetic ketoacidosis. The infection most frequently occurs in the rhinocerebral region and rapidly spreads, causing a swift demise. Rarely, the infection is confined to the cutaneous tissues. We describe a 31-year-old man seropositive for human T lymphotropic virus type I who had diabetic ketoacidosis with zygomycosis confined to the right arm. The lesion was presumed initially to be a bacterial infection but did not respond to conventional antimicrobial therapy. The arm lesion was cultured, and rhizopus arrhizus was isolated. The patient responded well to a combination of amphotericin b and extensive surgical debridements. Our case emphasizes the importance of maintaining a high index of suspicion of cutaneous zygomycotic infections in the impaired host, especially of those in patients with diabetes, who do not respond to initial antimicrobial treatment.- - - - - - - - - - ranking = 0.25keywords = bacterial infection (Clic here for more details about this article) |
3/6. Isolated renal mucormycosis: case report and review.The 15th reported case of isolated renal mucormycosis (infection of the kidney with fungus of the order mucorales, in the absence of infection elsewhere in the body) is presented. The patient was a 36-year-old human immunodeficiency virus-infected man, actively using iv drugs, who suffered 6 wk of flank pain and fever before diagnosis was made by percutaneous renal biopsy. He received 4 months of amphotericin b treatment, then no therapy for 6 months before dying with no evidence of mucormycosis. Isolated renal mucormycosis should be suspected in those with an underlying immunocompromising illness or history of iv drug use who have persistent flank pain and fever, but sterile urine cultures. Computed tomographic scanning with contrast should then be performed; findings of severe inflammation or bacterial infection, despite an indolent clinical course with sterile or nondiagnostic urine and blood cultures, are suggestive of isolated renal mucormycosis, and renal biopsy under computed tomographic guidance should be performed, despite the potential risk of disseminated infection. Although our patient was treated with amphotericin b alone, nephrectomy with or without amphotericin b therapy appears to be more likely to cure infection and relieve pain and constitutional symptoms.- - - - - - - - - - ranking = 0.25keywords = bacterial infection (Clic here for more details about this article) |
4/6. Fatal genitourinary mucormycosis in a patient with undiagnosed diabetes.We present what we believe is the first report in the world literature of penile necrosis due to mucormycosis, a rare and often fatal fungal infection. This case of rhizopus mucormycosis began with a penile lesion in a 27-year-old patient with undiagnosed diabetes; it led to necrosis of the phallus, lower urinary tract, rectum, and pelvic musculature and finally to death. Despite repeated aggressive surgical debridement in conjunction with medical therapy, we were unable to halt the progression of the fungal and synergistic bacterial infections.- - - - - - - - - - ranking = 0.25keywords = bacterial infection (Clic here for more details about this article) |
5/6. mucormycosis caused by rhizopus microsporus var. microsporus: cellulitis in the leg of a diabetic patient cured by amputation.mucormycosis accompanied the development of bacterial infection in the leg of a diabetic African-American man. Local injury, diabetic ketoacidosis, renal insufficiency, and antimicrobial therapy were factors that contributed to the pathogenesis of the mucormycosis. The cellulitis was caused in part by rhizopus microsporus var. microsporus and was cured by amputation. We report this unusual case of mucormycosis to emphasize the value of fungal identification, to illustrate a dramatic and successful clinical result, and to draw attention to an apparent role for bacterial infection and its treatment in the pathogenesis of mucormycosis. It is the third case report of mucormycosis in a human in which R. microsporus var. microsporus was definitively identified as the etiologic agent.- - - - - - - - - - ranking = 0.5keywords = bacterial infection (Clic here for more details about this article) |
6/6. mucormycosis of the vulva following bone marrow transplantation.mucormycosis is uncommon in bone marrow transplant recipients. Primary cutaneous mucor in any setting is unusual. It may mimic necrotizing bacterial infection particularly in patients with severe neutropenia. We report a case of vulvar mucormycosis in a transplant recipient. diagnosis depends on histological identification of fungal hyphae invading tissue and blood vessels.- - - - - - - - - - ranking = 0.25keywords = bacterial infection (Clic here for more details about this article) |