1/5. Weight problems in adolescence.Even the normal adolescent must incorporate into his body image radical changes in size, body proportions, and sexual characteristics. obesity and anorexia, which are commonplace, may be sensitive problems to deal with.- - - - - - - - - - ranking = 1keywords = size (Clic here for more details about this article) |
2/5. Macroprolactinemia in childhood and adolescence: a cause of hyperprolactinemia.Human prolactin consists of multiple forms of different sizes including three major prolactin (PRL) species, termed as little, big, and big-big PRL. If serum contains big-big PRL, it is termed macroprolactinemia; no symptoms of hyperprolactinemia develop due to low biological activity of big-big PRL. There are still few data regarding macroprolactinemia in children and adolescents. In this paper we describe six patients with macroprolactinemia, one of whom was asymptomatic and the other five either had headache, menstrual disturbance, short stature, increased hair growth or early puberty, compatible with high PRL levels. Two of the cases had microadenoma. Initial mean /- SD PRL levels of the patients were 75.2 /- 22.8 ng/ml (range: 42.3-105.2 ng/ml). Macroprolactin analysis revealed big-big PRL levels of the patients ranging between 21.6-98.6 ng/ml. It was noteworthy that bromocriptine (BRC) therapy started in three patients caused an abrupt decrease in PRL levels. It may be concluded that macroprolactinemia should be taken into account in the differential diagnosis of hyperprolactinemia in childhood and adolescence, whether or not they have relevant clinical symptoms.- - - - - - - - - - ranking = 1keywords = size (Clic here for more details about this article) |
3/5. Chromosomally competent ovarian failure at adolescence.Three female adolescents are presented with delayed or incomplete secondary sexual development due to primary ovarian failure. All three patients had normal blood leukocyte and ovarian tissue karyotypes. The importance of performing a diagnostic laparoscopy with ovarian biopsy in the setting of chromosome competent ovarian failure (CCOF) is emphasized.- - - - - - - - - - ranking = 1keywords = size (Clic here for more details about this article) |
4/5. Sensitivity to endogenous progesterone. Report of a case.A patient with a cyclic premenstrual eruption, clearing spontaneously with the menstrual flow, is reported. hypersensitivity to endogenous progesterone in this case was confirmed by positive intradermal and leukocyte migration inhibition tests. Treatment with conjugated estrogens was followed by remission of symptoms. The importance of awareness to the possibility of progesterone autoimmune mechanisms is emphasized.- - - - - - - - - - ranking = 1keywords = size (Clic here for more details about this article) |
5/5. Oligodontia of the permanent dentition in two sisters with polycystic ovarian syndrome: case reports.Oligodontia or severe hypodontia is a rare developmental dental anomaly commonly associated with syndromes and systemic abnormalities. This report presents two sister, aged 18 and 21, who collectively had 56 congenitally missing permanent teeth. Both patients exhibited pubertal hirsutism, menstrual disturbances, and enlarged ovaries with multicystic lesions defined ultrasonically. These features are consistent with the diagnosis of polycystic ovarian syndrome, a disease not previously linked to hypodontia. A genetic component of this condition is proposed. The significance of this entity is discussed and the importance of early diagnosis and treatment regimens are emphasized.- - - - - - - - - - ranking = 1keywords = size (Clic here for more details about this article) |