1/21. Non-Q wave acute myocardial infarction in acute meningococcemia in a 10-year-old girl.INTRODUCTION: Children with acute meningococcemia may have impaired myocardial function resulting in low cardiac output despite normal intravascular volume. Severe meningococcal infection has been associated with acute interstitial myocarditis, endocarditis, and pericarditis, but not with myocardial infarction. CASE: We present the case of a 10-year-old girl with positive family history for premature myocardial infarction who sustained an acute myocardial infarction temporally related to meningococcemia. DISCUSSION: This is the first pediatric case of non-Q wave acute myocardial infarction associated with purpura fulminans in meningococcemia. Similarly, the association of high troponin i levels and meningococcemia has not been described previously. Although, the patient's genetic predisposition for myocardial infarction might have been a potential contributing factor, there was no angiographic evidence of coronary artery disease in this patient. Thereby, other factors related to shock, endotoxin, microthrombi of meningococcemia, and their treatment might have been also contributing. We propose possible mechanisms for this rare but serious complication of meningococcemia and review the literature.- - - - - - - - - - ranking = 1keywords = pericarditis (Clic here for more details about this article) |
2/21. Meningococcal pericarditis in a 2-year-old child: reactive or infectious?pericarditis is an uncommon manifestation of infection of neisseria meningitidis. pericarditis may be caused by direct invasion or immune-complex-mediated (reactive) inflammation. We outline the case of a two-year-old girl with probable reactive pericarditis, review the cases reported in the English literature since 1966 and discuss the pathogenesis of meningococcal pericarditis.- - - - - - - - - - ranking = 6keywords = pericarditis (Clic here for more details about this article) |
3/21. Primary meningococcal arthritis in a prosthetic knee joint.neisseria meningitidis is known to cause a spectrum of diseases, including bacteraemia without sepsis, meningococcaemia without meningitis, meningitis with or without meningococcaemia, and chronic meningococcaemia. Less common manifestations of meningococcal infection include pharyngitis, pneumonia, pericarditis, urethritis and arthritis. To our knowledge, there have been no previous reports of N. meningitidis causing prosthetic joint infection. Herein, we report a case of primary meningococcal arthritis in a woman with a prosthetic knee joint. After surgical drainage the prosthesis was retained and the patient received appropriate and prolonged antibiotic treatment. The outcome was favourable, as with primary meningococcal arthritis affecting native joints.- - - - - - - - - - ranking = 1keywords = pericarditis (Clic here for more details about this article) |
4/21. pericarditis after meningococcal infection: case report of a child with two distinct episodes.pericarditis is a recognized consequence of meningococcal disease. The incidence among all age groups is 3 to 19%. Repeated episodes of pericarditis after meningococcal disease have been reported previously in two adults but not in children. We describe the clinical and laboratory features of a child with two distinct episodes of pericarditis after neisseria meningitidis serogroup C infection.- - - - - - - - - - ranking = 2keywords = pericarditis (Clic here for more details about this article) |
5/21. Meningococcal pericarditis and tamponade.We report the case of a 37-year-old female with a complex manifestation of serogroup C meningococcal disease. The patient presented with symptoms and signs of pneumonia, sepsis and diffuse intravascular coagulation. Moreover, she suffered from a culture-proven pyogenic pericarditis that deteriorated into cardiac tamponade. Immediate pericardiocentesis was successful and eventually the patient recovered.- - - - - - - - - - ranking = 5keywords = pericarditis (Clic here for more details about this article) |
6/21. W135 meningococcal pericarditis: report of two cases and review of the literature.pericarditis is a rare but recognized complication of meningococcal disease. After the 2000 and 2001 hajj in saudi arabia, a worldwide outbreak of meningococcal W135:2a:P1.2,5 (epidemic strain) was reported including the United Kingdom. Cases of meningococcal disease occurred in pilgrims and their household contacts; and community spread occurred among non-Muslims. Between July 2001 and January 2002, 2 children with pericarditis associated with W135 meningococcal disease were admitted to our hospital in east london.- - - - - - - - - - ranking = 5keywords = pericarditis (Clic here for more details about this article) |
7/21. Cytokine activation in purulent pericarditis caused by neisseria meningitidis serogroup C.Herein, we report a case of purulent pericarditis caused by neisseria meningitidis serogroup C in a previously healthy 5-year-old boy, which was detected in pericardial fluid by polymerase chain reaction. The concentrations of interleukin-6, interferon-gamma and interleukin-10 in pericardial fluid were notably increased compared with serum. The role of polymerase chain reaction, counterimmunoelectrophoresis and latex agglutination test in the diagnosis, as well as the participation of cytokines in the pathogenesis of meningococcal pericarditis, are discussed.- - - - - - - - - - ranking = 6keywords = pericarditis (Clic here for more details about this article) |
8/21. Purulent pericarditis caused by neisseria meningitidis serogroup C and confirmed through polymerase chain reaction.We here report the case of a previously healthy 20-y-old male with disseminated meningococcal disease and purulent pericarditis. polymerase chain reaction was used to identify neisseria meningitidis serogroup C as the causative agent in the pericardial fluid.- - - - - - - - - - ranking = 5keywords = pericarditis (Clic here for more details about this article) |
9/21. Pathophysiology of primary meningococcal pericarditis associated with neisseria meningitidis group C. A case report and review of the literature.pericarditis associated with neisseria meningitidis in the absence of meningitis or meningococcemia is an extremely rare event. We report herein a case of a 59-yr-old woman with primary meningococcal pericarditis caused by neisseria meningitidis group C. The patient responded to a course of penicillin therapy and recovery was uncomplicated. The pathophysiologic features underlying or contributing to the disease are discussed and the pertinent literature is reviewed.- - - - - - - - - - ranking = 5keywords = pericarditis (Clic here for more details about this article) |
10/21. Purulent pericarditis in children.Acute purulent pericarditis was treated successfully in five children between the ages of 27 months and 11 1/2 years during the past 5 years. The responsible organism was Hemophilus influenzae, type b, in two cases and Meningococcus, Pneumococcus, and coagulase-positive staphylococcus aureus in one case each. No primary source of infection could be identified in two patients. A high index of suspicion, combined with immediate echocardiograms and pericardiocentesis, led to the diagnosis. Immediate antibiotic therapy was instituted on the basis of the gram stain of the pericardial fluid. All five patients had a pericardial window established--four through subxyphoid approach and the fifth, because of a left pleural effusion, through a left thoracotomy. When the subxyphoid approach was used, sump drains were left for postoperative suction and irrigation. All five patients survived without sequalae during follow-up periods of from 18 months to 5 years. We advocate an aggressive approach to the diagnosis and treatment of this problem. This report documents the safety, ease, and effectiveness of the subxyphoid approach as a means of drainage.- - - - - - - - - - ranking = 5keywords = pericarditis (Clic here for more details about this article) |
| | Next -> |