1/2. A case of normotensive primary aldosteronism with hypopituitarism, epilepsy, and medullary sponge kidney.A 55-year-old man with normotensive primary aldosteronism, hypopituitarism, epilepsy, and medullary sponge kidney is reported. Seventeen years before admission, he had been noted to have hypokalemia associated with high potassium clearance, suppressed plasma renin activity, metabolic alkalosis, and normal blood pressure as well as low urinary excretion of 17-hydroxycorticosteroids. He kept normotensive in spite of hyperaldosteronism until nine months after the initiation of replacement therapy with glucocorticoid and thyroxine for hypopituitarism, when he became hypertensive. hypopituitarism seemed to play a role in keeping a normal blood pressure despite long-standing hyperaldosteronism.- - - - - - - - - - ranking = 1keywords = hyperaldosteronism (Clic here for more details about this article) |
2/2. hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension.hyperparathyroidism and hyperaldosteronism coexisted in association with medullary sponge kidneys in a 27-year-old woman with severe hypertension. A modest fall in systolic and diastolic pressure followed removal of a parathyroid adenoma. blood pressure was controlled with spironolactone therapy and restored to normal after removal of an aldosterone-secreting adrenal tumor. Elevated levels of aldosterone may have been responsible for the severe hypertension, while hypercalcemia may have had a synergistic effect on the arteriolar response to circulating vasoactive peptides.- - - - - - - - - - ranking = 0.5keywords = hyperaldosteronism (Clic here for more details about this article) |