1/166. lipoma of the corpus callosum.lipoma of the corpus callosum is a rare congenital condition, often asymptomatic, but which may present as epilepsy, hemiplegia, dementia, or headaches. This paper reviews the condition and reports the only two cases which are known to the Hospital for Sick Children, Great Ormond Street, london. The second case demonstrated the value of computerised axial tomography (EMI scan) in making the diagnosis and showing associated anomalies.- - - - - - - - - - ranking = 1keywords = headache (Clic here for more details about this article) |
2/166. Giant cervico-mediastinal lipoma. A clinical case.The lipoma is a circumscribed mesenchymal tumour originating from adipose tissue. The lesion is usually small and asymptomatic, and is most frequently located in the neck region. The case of a 77-year-old woman with chronic extrasystolic arrhythmia caused by a non-specified ischemic cardiopathy is reported. The woman presented a swelling at the front of her neck, observed for the first time about 6 months previously. This swelling progressively increased in size, provoking dysphagia, dysphonia, persistent cough, dyspnea, light jugular turgor and palpitations. Chest x-rays showed and opaque area at the front of the neck, which extended beyond the jugular incisure by about 2 cm. NMR of the neck showed a gross lipomatous formation at the front, mainly of the left, continuing in the front mediastinal region; the trachea was dislocated to the right and compressed at the back; the vasculo-nervous fasciculus, especially on the left, was compressed and enveloped by the adipose formation. The Holter test confirmed the presence of ventricular and supra-ventricular extrasystoles. Surgery was carried out under local anaesthesia because the displacement of the laryngo-tracheal axes precluded intubation. Histological analysis of the 9 x 4 x 2.2 cm mass confirmed the diagnosis of lipoma. After removal of the mass all the symptoms, which had been provoked by compression, as well as the cardiac arrhythmias disappeared. The prompt disappearance of the latter was particularly surprising. The possibility of the external compression of the nervous structures of the neck should be taken into consideration in cases of ventricular arrhythmia of unknown origin, and systematic study of the region carried out.- - - - - - - - - - ranking = 3.9916652219203keywords = back (Clic here for more details about this article) |
3/166. Squamous cell carcinoma and lipomatous pseudohypertrophy of the pancreas.A 68-year-old woman who had been treated for non-insulin-dependent diabetes mellitus for the past 20 years was admitted to hospital because of abdominal pain and weight loss. Radiological investigation revealed a tumour in the body of the pancreas and numerous intraductal calcifications in both the tail and the head of the pancreas. Left-sided pancreatectomy was performed to remove the tumour. The resection specimen showed fatty enlargement of the parenchyma and numerous intraductal calcifications in the tissue adjacent to the tumour, which was 7 cm in diameter and was found to be a primary squamous cell carcinoma with a spindle cell component. There was also lipomatous pseudohypertrophy.- - - - - - - - - - ranking = 30.876209783935keywords = abdominal pain (Clic here for more details about this article) |
4/166. teratoma in the region of adrenal gland: a unique entity masquerading as lipomatous adrenal tumor.BACKGROUND: The aim of this study was to establish the clinical and pathologic aspects of 3 atypical lipomatous lesions in the region of the adrenal gland. methods: Three young Chinese patients (ages 18, 18, and 37 years) were seen for nonspecific back pain. Radiologic examination revealed a lipomatous lesion in the region of the adrenal gland, and hormonal assessment was normal. Calcification was noted in 2 of the 3 lesions. adrenalectomy was performed because of the size (diameter 7.5, 10, 11 cm) of the tumors with suspected local symptoms. RESULTS: On gross examination 2 tumors were cystic and 1 was solid. In all 3 patients the diagnosis was mature teratomas. The tumors were composed of mature tissues arising from more than 1 germinal layer. There was no evidence of immature elements or malignancy. adipose tissue was the predominant component in the tumors. There was no evidence of recurrent diseases in all these patients during follow-up. CONCLUSIONS: To our knowledge, this is the first report of teratomas occurring in the adrenal region. teratoma should clinically and radiologically be included in the differential diagnoses of lipomatous adrenal lesions. Excision of the teratoma is advocated.- - - - - - - - - - ranking = 7.1540811147422keywords = back, back pain (Clic here for more details about this article) |
5/166. Atypical lipomatous tumors with smooth muscle differentiation: report of two cases.Two cases of soft-tissue atypical lipomatous tumors with areas of smooth muscle cell differentiation are presented. The patients were a 72-year-old man (Case 1) and a 62-year-old woman (Case 2); their neoplasms were located in the left inguinal region and on the chest, respectively. The adipocytic component in Case 1 contained cells with nuclear atypism and lipoblasts. Case 2 showed only slight nuclear atypism and lacked any lipoblasts. Smooth muscle fascicles were composed of well-differentiated cells with a few mitoses having none or only a slight atypism. They expressed muscle-specific actin and desmin in both cases. No recurrence was recorded during the follow-up time.- - - - - - - - - - ranking = 4.2741755166437keywords = chest (Clic here for more details about this article) |
6/166. Ruptured giant intrathoracic lipoblastoma in a 4-month-old infant: CT and MR findings.BACKGROUND: We describe a 4-month-old infant with a ruptured intrathoracic lipoblastoma arising from the parietal pleura and associated with a pleural effusion. OBJECTIVE: The clinical presentation was rapidly evolving respiratory distress. The chest radiograph showed a large mass and a pleural effusion in the right thoracic cavity. CT demonstrated an inhomogeneous low-attenuation mass which was 7 cm in diameter and which showed areas of enhancement after intravenous contrast medium. MRI showed a fatty intrathoracic mass with intratumoral streaks and whorls, which were attributed to loose fibrovascular connective tissue on pathological examination. RESULTS: thoracotomy and pathological examination revealed a ruptured intrathoracic lipoblastoma arising from the parietal pleura. CONCLUSION: The pleural effusion might have suggested rupture of the tumour.- - - - - - - - - - ranking = 4.2741755166437keywords = chest (Clic here for more details about this article) |
7/166. Midline developmental anomalies with lipomas in the corpus callosum region.Three children with complete or partial callosal aplasia and intracranial lipoma in the corpus callosum region were investigated. Two lipomas were tubulonodular; one replaced the entire corpus callosum structure. Accompanying anomalies affected the cingulate gyrus, septum pellucidum, and choroid plexus. In one case, diagnosis was made in utero in the 25th gestational week by ultrasonography; in the second case it was made on the first day of life, also by screening ultrasonography. Two children had mild spastic distal diparesis; one complained of chronic headache. electroencephalography showed no abnormalities; epilepsy anamnesis was negative. Somatosensory and visual evoked potentials showed prolonged conduction in two cases. Surgery was not indicated. Because of the risk of developing epileptic seizures, regular electroencephalographic follow-up investigations are essential.- - - - - - - - - - ranking = 1keywords = headache (Clic here for more details about this article) |
8/166. thoracic wall lipoblastoma: a case report and review of histopathology and cytogenetics.A rare case of a successfully excised intra- and extrathoracic lipoblastoma of the anterior chest wall in a 13-month-old female infant is reported. Histopathology and cytogenetical analysis established the diagnosis of a lipoblastoma. The differential diagnosis, histology and cytogenetical evaluation of lipomatous neoplasms are discussed. Karyotypic analysis may be of use in diagnostically difficult cases owing to the characteristic alterations in 18q11-13. A complete resection of lipoblastomas is feasible and advantageous with no need for a mutilating radical excision.- - - - - - - - - - ranking = 4.2741755166437keywords = chest (Clic here for more details about this article) |
9/166. Diagnostic pitfalls in fine needle aspiration cytology of pleomorphic lipoma. A case report.BACKGROUND: Pleomorphic lipoma is an unusual pseudosarcomatous condition with characteristic morphology. Despite its pleomorphic appearance, it follows a benign course and does not recur or metastasize if completely excised. CASE: A 66-year-old man presented with swelling in the back of the neck of approximately six months' duration. The focally cellular aspirate revealed round to oval, hyperchromatic cells, rare multinucleated cells and fragments of mature adipose tissue. On initial evaluation, the smear pattern suggested a malignant neoplasm. However, upon review of the cytologic material along with histology, the characteristic pattern, including floret cells, was recognized. CONCLUSION: The rarity of pleomorphic lipoma and the atypical cellular features of the aspirate can cause difficulty in diagnosing this entity. awareness of this rare but not-uncommon entity, along with clinical correlation, is crucial in arriving at the correct diagnosis.- - - - - - - - - - ranking = 3.9916652219203keywords = back (Clic here for more details about this article) |
10/166. Thymohemangiolipoma, a rare histologic variant of thymolipoma: a case report and review of the literature.We report a case of a thymic neoplasm in an 18-year-old woman who presented with chest discomfort and an anterior mediastinal mass. The surgically resected tumor showed abundant adipose tissue admixed with thymic tissue and numerous medium-caliber blood vessels. We consider this tumor a rare variant of thymolipoma and designate it as thymohemangiolipoma. Because of its benign nature, it should be distinguished from other mediastinal lesions.- - - - - - - - - - ranking = 18.586647356162keywords = discomfort, chest (Clic here for more details about this article) |
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