1/11. Intracystic hemorrhage with spontaneous rupture of liver cyst complicated by infection: a case report.A 78-year-old man who was being followed-up for a liver cyst was admitted to Asakayama General Hospital because of the sudden onset of severe right hypochondralgia and fever, with a preceding dull pain in the right upper quadrant of the abdomen of four 'days' duration. Computed tomography revealed remarkable enlargement of the liver cyst. We diagnosed intracystic hemorrhage and spontaneous rupture of the liver cyst. As we diagnosed bacterial infection in the ruptured cyst, transhepatic cystic drainage was performed. After improving the clinical status of the patient, we injected ethanol into the cyst, inducing a significant decrease in its size. There has been a few previous reports of intracystic hemorrhage and spontaneous rupture of a liver cyst complicated by infection. Transhepatic cyst drainage combined with antibiotic therapy and intracystic ethanol injection may be a useful and minimally invasive method for liver cysts with these complications, especially in compromised patients.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
2/11. Expanded-spectrum beta-lactamase producing klebsiella pneumoniae-related peritonitis in a patient on peritoneal dialysis.While hospitalized for pneumonia with ventilator-dependent respiratory failure, a 45-year-old man on continuous ambulatory peritoneal dialysis (CAPD) had nosocomial peritonitis secondary to infection by expanded spectrum beta-lactamase producing klebsiella pneumoniae (ESBL-Kp). He was treated successfully with a 3-week course of intraperitoneal (IP) flomoxef therapy without subsequent relapse, loss of peritoneal catheter, ultrafiltration failure, or dialysis inadequacy. The International consensus Panel recommends IP ceftazidime as the treatment of choice for CAPD patients suffering Klebsiella species-related peritonitis. However, the most appropriate form of IP antibiotic therapy and the outcomes for expanded-spectrum beta-lactamase (ESBL)-producing bacteria-related peritonitis for CAPD patients have not been established yet. Further, the ability to correctly report minimal inhibitory concentrations (MICs) of ceftazidime for ESBL bacteria in the resistant range varies between laboratories, making the diagnosis of ESBL-Kp-related CAPD peritonitis more complex and difficult. Thus, it appears reasonable to suggest that its incidence is probably underestimated and its significance ignored. The authors suggest that a 3-week IP treatment with flomoxef, a synthesized oxacephem, with loading and maintenance doses of 250 and 125 mg/L, respectively, is effective and safe for ESBL-Kp-related peritonitis in these patients. ESBL producing bacterial infection should be considered as a possible cause of overt CAPD-related peritonitis. Early detection of ESBLB pathogens and institution of effective antibiotic treatment may improve the prognosis.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
3/11. Transfusion-transmitted klebsiella pneumoniae fatalities, 1995 to 2004.Transfusion-transmitted bacterial sepsis is the third most common cause of transfusion-related fatalities reported to the food and Drug Administration. Between October 1, 1995, and September 30, 2004, there were 665 reported transfusion fatalities. Eighty-five (13%) deaths were due to transfusion-transmitted bacterial infections, of which 58 (68%) were due to gram-negative organisms. The most common gram-negative organism associated with transfusion-transmitted deaths after receipt of platelets was klebsiella pneumoniae. This article summarizes retrospectively the case series of deaths due to transfusion-transmitted K pneumoniae infection, reported to the food and Drug Administration, 1995 to 2004. There were 12 deaths due to transfusion-transmitted K pneumoniae infection with 7 (58%) of the 12 cases occurring in 2002. Eleven deaths were caused by the transfusion of contaminated platelets and 1 death attributed to contaminated red blood cells. Extensive review of the seven 2002 fatality reports did not identify a common (shared) lot for items used during collection or processing of the blood product. In conclusion, in cases of suspected transfusion-transmitted septicemia, broad spectrum antibiotic coverage including coverage of gram-negative organisms should be considered. Strict adherence to infection control measures while collecting, processing, and handling all blood and blood components in both the clinical settings and in the laboratory should be followed. Further development of simple and effective test procedures for detecting bacteria in the blood is needed.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
4/11. Fatal klebsiella pneumoniae meningitis and emphysematous brain abscess after endoscopic variceal ligation in a patient with liver cirrhosis and diabetes mellitus.Procedure-related bacterial infections may complicate esophageal variceal ligation in cirrhosis patients. Here, we report a 58-year-old man with underlying diabetes and liver cirrhosis who developed klebsiella pneumoniae meningitis and brain abscess with gas formation in brain parenchyma and ventricles after this procedure. Despite administration of appropriate antimicrobial therapy, he became comatose on the 3rd day of acute illness and died on the 4th day of hospitalization. This case highlights the indication for antimicrobial prophylaxis in cirrhotic patients with gastrointestinal bleeding, and the need for early and heightened awareness of central nervous system infections in cirrhotic patients with hepatic encephalopathy.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
5/11. Detection of bacterial infection of the pancreatic ducts in patients with pancreatitis and pancreatic cancer during endoscopic cannulation of the pancreatic duct.bacterial infections of the pancreas and bacteremia may occur during episodes of pancreatitis. Detection of bacterial infections of the pancreas in the past has required laparotomy. The present study was undertaken to determine whether bacterial infection of the pancreas occurred during nonsuppurative pancreatitis. During endoscopic cannulation of the main pancreatic duct, secretin was administered intravenously and pancreatic juice aspirated from within the duct was cultured. bacterial infections were detected in 11 of 35 patients with pancreatitis and 3 of 5 with pancreatic cancer. The pancreatic juice was sterile in 25 controls. Cultures from the common bile duct in 9 controls were also sterile whereas 4 of 6 with pancreatitis showed infected bile. The infecting organisms were principally gram-negative and the infections were usually polymicrobial. Antibiotics, where used, successfully eradicated the infecting organisms but did not appear to affect the patient's clinical course.- - - - - - - - - - ranking = 6keywords = bacterial infection (Clic here for more details about this article) |
6/11. Polymicrobial septicemia associated with rhabdomyolysis, myoglobinuria, and acute renal failure.myoglobinuria and renal failure resulting from bacterial infection have only rarely been reported. To our knowledge, we describe the first reported case of polymicrobial septicemia resulting in rhabdomyolysis and myoglobinuric renal failure. Renal failure secondary to myoglobinuria has an excellent prognosis; in our patient, recovery was complete. The frequency of rhabdomyolysis, myoglobinuria, and renal failure in septicemia is unknown and can only be determined by an increased awareness of this potential complication of septicemia.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
7/11. Results of bacteriophage treatment of suppurative bacterial infections. III. Detailed evaluation of the results obtained in further 150 cases.The results of phage therapy applied in further 150 cases of suppurative bacterial infections were analyzed. Positive therapeutic results were obtained in 137 cases (91.3%). The results obtained confirmed the previous findings on great effectiveness of bacteriophages in the treatment of septic infections, spontaneous or postoperative, caused by pyo genic Staphylococci, Klebsiella, escherichia, proteus and pseudomonas.- - - - - - - - - - ranking = 5keywords = bacterial infection (Clic here for more details about this article) |
8/11. Pulmonary stronglyoidiasis complicating therapy with corticosteroids. Report of a case with secondary bacterial infections.We report a case of pulmonary strongloidiasis which occurred after high-dose corticosteroid therapy. Our patient responded very well to treatment with thiabendazole, despite the fact that the steroids were contined throughout his entire hospital course. Further complications included pseudomonas meningitis and klebsiella pneumoniae pneumonia, both of which resolved with appropriate treatment.- - - - - - - - - - ranking = 4keywords = bacterial infection (Clic here for more details about this article) |
9/11. Clinical efficacy of cefoxitin in the treatment of head and neck infections.cefoxitin sodium, a new cephamycin antibiotic, is active against many aerobic and anaerobic bacteria. Four patients with infections of the head and neck (otitis externa with cellulitis, parotiditis, tracheitis, and facial cellulitis), who had failed to respond to initial antibiotic regimens, responded satisfactorily to cefoxitin therapy. No adverse effects were noted in any of these patients. Results of this report suggest cefoxitin is a safe and well-tolerated antibiotic that is efficacious in the treatment of head and neck bacterial infections that are sensitive to this drug.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
10/11. vancomycin therapy for infective endocarditis.The use of vancomycin is increasing for the treatment of serious life-threatening staphylococcal and other bacterial infections, including infective endocarditis, in patients who are allergic to the penicillins. The literature through 1978 reveals approximately 55 cases of infective endocarditis treated with vancomycin alone or with combined antibiotic therapy. Many of these 55 patients were treated by different clinicians, were given variable regimens of therapy, received other therapy before vancomycin, had associated valve replacement; various amounts of data were provided for the reported cases. A summary of these reports indicates a cure in 48 (87%) of the 55 patients. Recent in vitro and in vivo animal and patient data indicate that vancomycin alone or as part of combined therapy is bactericidal and curative in patients allergic to penicillin for infective endocarditis caused by staphylococci and streptococci-both enterococcal and nonenterococcal (streptococcus bovis and viridans group streptococci) infections. In this study, 10 patients with infective endocarditis were treated with vancomycin or combined therapy; seven were cured. Five of the 10 patients with infective endocarditis caused by viridans streptococci were cured with combined vancomycin-streptomycin given in short-term therapy for two weeks.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
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