1/2. adult penicillinase-producing gonococcal keratoconjunctivitis.The case is described of a 22-year-old man who presented with ulcerative keratitis as a complication of conjunctivitis that was caused by penicillinase-producing neisseria gonorrhoeae. The need for first-line treatment with antibiotic agents that are resistant to beta-lactamase breakdown is discussed.- - - - - - - - - - ranking = 1keywords = gonorrhoeae (Clic here for more details about this article) |
2/2. neisseria gonorrhoeae keratoconjunctivitis.Clinical and laboratory findings of 47 patients with ocular infections secondary to neisseria gonorrhoeae during a 5 1/2-year period were reviewed. In 16 patients (34%), corneal involvement was noted. Six of these patients had a severe ulcerative keratitis resulting in permanent visual loss and five required surgery for a corneal perforation. patients with corneal involvement were older and presented later in the course of their disease than patients with isolated conjunctival involvement (P less than 0.005). An out-patient regimen of intramuscular antibiotics (either penicillin, cephalosporin, or spectinomycin [Trobicin]) appeared to be effective for infections limited to the conjunctiva in adults. If a topical antibiotic ointment is used in addition to parenteral antimicrobial agents, the authors' laboratory sensitivities suggest that erythromycin may be the drug of choice.- - - - - - - - - - ranking = 5keywords = gonorrhoeae (Clic here for more details about this article) |