1/3. Is phenytoin administration safe in a hypothermic child?A male neonate with a Chiari malformation and a leaking myelomeningocoele underwent ventriculoperitoneal shunt insertion followed by repair of myelomeningocoele. During anaesthesia and surgery, he inadvertently became moderately hypothermic. Intravenous phenytoin was administered during the later part of the surgery for seizure prophylaxis. Following phenytoin administration, the patient developed acute severe bradycardia, refractory to atropine and adrenaline. The cardiac depressant actions of phenytoin and hypothermia can be additive. Administration of phenytoin in the presence of hypothermia may lead to an adverse cardiac event in children. As phenytoin is a commonly used drug, clinicians need to be aware of this interaction.- - - - - - - - - - ranking = 1keywords = anaesthesia (Clic here for more details about this article) |
2/3. Delayed recovery following atracurium: a case report.A 41-year-old woman received a total of 19 mg (0.6 mg kg-1) of atracurium over a 2-h period of general anaesthesia for abdominal surgery. Spontaneous respiration could not be achieved with neostigmine reversal. The temperature was found to be below 35 degrees C, and this delay in recovery is attributed to unrecognized accidental hypothermia.- - - - - - - - - - ranking = 1keywords = anaesthesia (Clic here for more details about this article) |
3/3. Delayed recovery from general anaesthesia.A case of postoperative coma associated with diabetes insipidus and hypothermia is presented. Some recommendations are offered for the future management of similar cases.- - - - - - - - - - ranking = 4keywords = anaesthesia (Clic here for more details about this article) |