1/5. A fatal case of fulminant myocarditis with human herpesvirus-6 infection.We report a case of fulminant myocarditis after steroid pulse therapy for acute hepatitis. Serological studies demonstrated a four-fold increase in the antibodies against human herpesvirus-6 (HHV-6) IgG, and a PCR showed the existence of HHV-6 virus dna. HHV-6 virus dna was also isolated from the liver and the heart. We believe that exacerbation of fulminant myocarditis was probably associated with the reactivation of HHV-6 due to the immunosuppressive state of the host.- - - - - - - - - - ranking = 1keywords = herpesvirus (Clic here for more details about this article) |
2/5. Chronic graft-versus-host disease after hematopoietic cell transplantation presenting as an acute hepatitis.A variety of illnesses involving the gut and liver follow hematopoietic cell transplantation (HCT). A 20 yr-old white male developed severe acute hepatitis 36 wk (day 252) after matched, unrelated, allogeneic HCT for chronic myelogenous leukemia (CML). Mild skin graft-versus-host disease (GVHD) had occurred at about 20 wk (day 140) after transplant. liver biopsy showed bile duct injury and a diffuse lobular injury pattern most consistent with a GVHD variant and not reminiscent of drug-induced or viral hepatitis. No findings suggestive of herpesvirus, adenovirus, or varicella-zoster virus were found. High-dose steroids resulted in marked improvement of his liver enzyme levels. We report this patient as representing the acute hepatitic presentation of chronic GVHD of the liver.- - - - - - - - - - ranking = 0.2keywords = herpesvirus (Clic here for more details about this article) |
3/5. Disseminated herpesvirus infection. association with primary genital herpes in pregnancy.A patient with primary herpes simplex virus (HSV) type 2 genital infection had dissemination in the 37th week of her first pregnancy. This was manifested by severe hepatitis, pancreatitis, and genital lesions. Temporary improvement followed the delivery of a healthy infant by cesarean section. encephalitis became evident on the third postpartum day, and recovery was complicated by profound bradycardia, possibly due to viral myocarditis. vidarabine was administered for seven days, and the patient survived with only mild neurologic sequellae. To our knowledge, this the fourth reported case of disseminated herpesvirus infection in pregnancy and the first due to HSV type 2. pregnancy must be considered as a possible predisposing factor in dissemination of primary HSV infection.- - - - - - - - - - ranking = 1keywords = herpesvirus (Clic here for more details about this article) |
4/5. Fatal herpetic hepatitis in pregnancy.Disseminated herpetic infections are becoming more commonly reported during pregnancy. Such infections almost always occur in the third trimester and are usually associated with a primary infection, which serves as a portal of entry. Because of the high fetal and maternal mortality associated with this condition, early diagnosis and treatment are essential. Disseminated herpesvirus infection must be considered whenever a pregnant patient has herpetic mucocutaneous lesions, vague systemic symptoms, or evidence of massive hepatic dysfunction.- - - - - - - - - - ranking = 0.2keywords = herpesvirus (Clic here for more details about this article) |
5/5. Fatal disseminated herpesvirus infection with hepatitis. A peritoneal fluid cytologic warning.A 19-year-old man died of a disseminated herpesvirus infection. Microscopic examination of a peritoneal fluid specimen revealed cellular changes characteristic of a herpetic process, and an autopsy confirmed widespread herpes simplex virus type II infection. Viral infections may be diagnosed by cytologic examination of body fluid specimens.- - - - - - - - - - ranking = 1keywords = herpesvirus (Clic here for more details about this article) |