Cases reported "Hemorrhage"

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1/4. An autopsy case of intramedullary venous malformation of the spinal cord with spreading hematomyelia.

    A 23-year-old Japanese woman experienced sudden severe shoulder pain, and subsequently died of cardiorespiratory arrest after an 8-day course of illness. autopsy revealed a venous malformation in the spinal cord at the C6 level with fresh massive hemorrhage showing widespread rostrocaudal extension. The upper limit of the hemorrhage was in the left gracile nucleus of the medulla oblongata, and the lower limit was in the left posterior horn of the spinal cord at L4. The hemorrhage extended through the spinal cord, involving the left posterior horn and intermediate zone of the gray matter and the ventral part of the posterior funiculus. The mechanism of the extension of the hemorrhage and the pathogenesis of the spinal venous malformation are discussed.
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keywords = nucleus
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2/4. The clinical and computed tomographic features of cerebellar peduncular hemorrhage.

    Three patients with medial ventral cerebellar peduncular hemorrhages presented with a characteristic syndrome. This included (1) ipsilateral ataxia, (2) lower motor neuron type facial weakness, and (3) ipsilateral gaze paresis. The gaze paresis could not be overcome with a doll's head maneuver. The findings are explained by compression of the facial colliculus, with involvement of the sixth nerve nucleus and the middle cerebellar peduncle. Two patients were hypertensive; one was normotensive, and no etiology was identified with angiography. Of 40 patients with cerebellar hemorrhage seen at our institution, only those with medial cerebellar peduncular hematomas demonstrated this clinical triad, and we have not seen this clinical triad in other pathologic conditions. The diagnosis of a small medial cerebellar peduncular hemorrhage was established by CT. In two patients, repeat CT showed complete hematoma resolution. The patients shared a favorable prognosis.
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keywords = nucleus
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3/4. Haemorrhage in neonatal hepatic necrosis due to herpes infection.

    A case of early neonatal severe bleeding and persistent hypoglycemia with a fatal outcome is reported. The autopsy examination revealed the features of neonatal hepatic necrosis. Further study by the electron microscopy indicated the presence of herpes type particles in the nucleus and cytoplasm of the remaining liver cells. Serological study of the maternal blood, post partum, revelaed positive reaction to herpes simplex virus type 2 at low titer. It is believed that intrauterine herpes infection was responsible for the severe hepatic damage manifesting in complex clinical findings.
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keywords = nucleus
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4/4. Medial thalamic hemorrhage with amnesia.

    Three patients had amnesia and confusion as presenting features of thalamic hemorrhage. They had a relatively benign clinical appearance and lacked characteristics of the syndrome usually associated with thalamic hemorrhage. We reviewed hypotheses regarding a mechanism for the amnesic syndrome and concluded that lesions involving the medial thalamic nucleus were responsible for the amnesia observed.
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keywords = nucleus
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