1/7. escherichia hermannii infection of a cephalohematoma: case report, review of the literature, and description of a novel invasive pathogen.We describe a neonate with bacterial infection of a cephalohematoma by escherichia hermannii and with meningitis. We review the literature on infected cephalohematomas and E. hermannii and document the first case of invasive disease due to this pathogen.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
2/7. Intracystic hemorrhage with spontaneous rupture of liver cyst complicated by infection: a case report.A 78-year-old man who was being followed-up for a liver cyst was admitted to Asakayama General Hospital because of the sudden onset of severe right hypochondralgia and fever, with a preceding dull pain in the right upper quadrant of the abdomen of four 'days' duration. Computed tomography revealed remarkable enlargement of the liver cyst. We diagnosed intracystic hemorrhage and spontaneous rupture of the liver cyst. As we diagnosed bacterial infection in the ruptured cyst, transhepatic cystic drainage was performed. After improving the clinical status of the patient, we injected ethanol into the cyst, inducing a significant decrease in its size. There has been a few previous reports of intracystic hemorrhage and spontaneous rupture of a liver cyst complicated by infection. Transhepatic cyst drainage combined with antibiotic therapy and intracystic ethanol injection may be a useful and minimally invasive method for liver cysts with these complications, especially in compromised patients.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
3/7. Blunt force injury of the abdomen complicating previously undiagnosed peliosis hepatis in a 2-year-old female.peliosis hepatis is an abnormal accumulation of blood-filled lakes in the liver that is most commonly seen in adults and is generally associated with chronic wasting diseases, use of androgenic steroids or bacterial infection. Few cases have been reported in children. We report a case of a 2-year-old female with no past medical history who presented with homicidal blunt force abdominal injury. The autopsy revealed lacerations in the liver and previously undiagnosed peliosis hepatis.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
4/7. Acute hemorrhagic edema of infancy associated with herpes simplex type 1 stomatitis.Acute hemorrhagic edema of infancy is a benign leukocytoclastic vasculitis occurring in children younger than 2 years. The etiology is unknown. Viral or bacterial infections, immunizations, and the use of several medications, mainly antibiotics, may be involved in the pathogenesis. We report the first instance of this disease associated with herpesvirus type 1 stomatitis.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
5/7. The hemorrhagic fevers of Southern africa with special reference to studies in the South African Institute for Medical research.In this review of studies on the hemorrhagic fevers of Southern africa carried out in the South African Institute for Medical research, attention has been called to occurrence of meningococcal septicemia in recruits to the mining industry and South African Army, to cases of staphylococcal and streptococcal septicemia with hemorrhagic manifestations, and to the occurrence of plague which, in its septicemic form, may cause a hemorrhagic state. "Onyalai," a bleeding disease in tropical africa, often fatal, was related to profound thrombocytopenia possibly following administration of toxic witch doctor medicine. Spirochetal diseases, and rickettsial diseases in their severe forms, are often manifested with hemorrhagic complications. Of enterovirus infections, Coxsackie B viruses occasionally caused severe hepatitis associated with bleeding, especially in newborn babies. Cases of hemorrhagic fever presenting in February-March, 1975 are described. The first outbreak was due to marburg virus disease and the second, which included seven fatal cases, was caused by rift valley fever virus. In recent cases of hemorrhagic fever a variety of infective organisms have been incriminated including bacterial infections, rickettsial diseases, and virus diseases, including Herpesvirus hominis; in one patient, the hemorrhagic state was related to rubella. A boy who died in a hemorrhagic state was found to have congo fever; another patient who died of severe bleeding from the lungs was infected with leptospira canicola, and two patients who developed a hemorrhagic state after a safari trip in Northern botswana were infected with trypanosoma rhodesiense. An illness manifested by high fever and melena developed in a young man after a visit to zimbabwe; the patient was found to have both malaria and marburg virus disease.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
6/7. Idiopathic spontaneous tonsillar haemorrhage.Since the advent of antibiotics major spontaneous tonsillar haemorrhage is extremely rare. The causes are usually ascribed to vessel wall erosion secondary to bacterial infection or infectious mononucleosis. We report the case of a 20-year-old female, presenting to the ENT department with tonsillar bleeding in the absence of any identifiable infective or traumatic process.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
7/7. Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins.Leukocyte adhesion deficiency (LAD) is characterized by the inability of leukocytes, in particular neutrophilic granulocytes, to emigrate from the bloodstream towards sites of inflammation. Infectious foci are nonpurulent and may eventually become necrotic because of abnormal wound healing. LAD-1 is characterized by the absence of the beta2 integrins (CD11/CD18) on leukocytes. When expression is completely absent, patients often die within the first year. However, low levels of beta2 expression may result in a milder clinical picture of recurrent infection, which offers a better prognosis. In this paper, we describe the in vivo and in vitro findings on a patient with clinical features of a mild LAD-1 disorder, i.e., suffering from bacterial infections without apparent pus formation in the presence of a striking granulocytosis, showing no delayed-type hypersensitivity reaction upon skin testing, no specific antibody generation, but normal in vitro T cell proliferation responses after immunization. Expression levels of CD11/CD18 proteins were completely normal, but leukocyte activation did not result in CD11/ CD18 activation and high-avidity ligand-binding. in vitro chemotaxis and endothelial transmigration of the neutrophils as well as leukocyte aggregation responses were almost absent. On the other hand, beta1 and beta3 integrin-mediated adhesion functions were completely normal. During follow-up, a bleeding tendency related to decreased beta3 activation became clinically apparent, different from previously described cellular adhesion molecule variants. Therefore, this is the first well-documented case of a clinical combined immunodeficiency syndrome that results from nonfunctional CD11/CD18 molecules, and thus designated LAD-1/ variant.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |