1/44. Delayed deterioration of hearing following bacterial meningitis.Bacterial meningitis is an important cause of acquired sensorineural deafness in childhood. deafness following meningitis may be progressive. Previous reports have shown deterioration in hearing up to 12 years after the illness. We present two cases of sensorineural deafness following meningitis. Severe to profound sensorineural hearing losses were detected immediately after meningitis in these patients. The hearing subsequently deteriorated in both cases. Deterioration in hearing thresholds occurred 17 years after the illness in one case. In the other patient the hearing got progressively worse three years after meningitis. She subsequently required a cochlear implant.- - - - - - - - - - ranking = 1keywords = meningitis (Clic here for more details about this article) |
2/44. hearing loss associated with large internal auditory meatus: a report of five paediatric cases.This paper describes the abnormality of a large internal auditory meatus (LIAM). Computed tomography (CT) scans show the otic capsule to be affected by a widened, bulbar internal auditory meatus with loss of or reduction of the bony wall dividing the lateral fundus of the meatus from the cochlea. The vestibule is abnormally dilated. We report five cases of children with LIAM and profound hearing loss. Three of these children are girls and two children were boys. Three had congenital progressive hearing loss, one of these had an accompanying large vestibular aqueduct and dysplasia of the cochlea. Two patients had had meningitis resulting in profound loss.- - - - - - - - - - ranking = 0.11111111111111keywords = meningitis (Clic here for more details about this article) |
3/44. syndrome of recurrent meninigitis due to congenital perilymph fistula with two different clinical presentations.Recurrent meningitis secondary to a congenital labyrinthine anomaly is a rare clinical entity, diagnosis of which is dependent upon certain clinical, radiological and intraoperative features. In the following report we describe two children with congenital labyrinthine fistula and recurrent meningitis whose clinical presentation, radiological features and intraoperative findings were dissimilar and thus, illustrative of two different ways of presentation of this rare disorder. While one had a classical Mondini defect and unilateral hearing loss, the other had normal audiometric and radiographic findings. The fistulae were successfully closed via a tympanotomy approach in both the patients.- - - - - - - - - - ranking = 0.22222222222222keywords = meningitis (Clic here for more details about this article) |
4/44. Tuberculous meningitis presenting as sensorineural hearing loss.We report a 60-year-old male who presented to the Otorhinolaryngology department with an acute unilateral sensorineural hearing loss associated with fever and night sweats. The diagnosis of tuberculous meningitis was made. Unilateral sensorineural hearing loss as a presenting symptom of tuberculous meningitis has not been previously reported.- - - - - - - - - - ranking = 0.66666666666667keywords = meningitis (Clic here for more details about this article) |
5/44. Cryptococcal meningitis: implications for the otologist.Cryptococcal meningitis can present to the otologist with hearing loss and vestibular dysfunction. A man with cryptococcal meningitis presenting with bilateral profound sensorineural hearing loss and vestibular dysfunction is described. The difficulty in arriving at the diagnosis and consequences of misdiagnosis are discussed. Histological and clinical studies suggest that the cochlear nerve is likely to be damaged in patients who have deafness associated with this disease. Retrocochlear damage may result in cochlear implantation having a poor outcome.- - - - - - - - - - ranking = 0.66666666666667keywords = meningitis (Clic here for more details about this article) |
6/44. Successful cochlear implantation in a child after recovery from a head and neck malignancy: a case report.We present the case of a successful pediatric cochlear implantation that was carried out following bilateral perilingual deafness caused by meningitis during the treatment of a childhood malignant tumor. A rhabdomyosarcoma localized in the frontobasal area was removed from the child at the age of 2 years. He then received 11 months of postoperative cytostatic treatment. A purulent meningitis developed at the end of the chemotherapy, resulting in a major-grade, bilateral sensorineural hearing loss (practically a perilingual deafness). After 6 tumor-free years and a meticulous preoperative assessment, a Nucleus 24 M cochlear implant was successfully implanted in the child's left ear. Two years after the operation, the child shows excellent hearing results and moderate speech development.- - - - - - - - - - ranking = 0.22222222222222keywords = meningitis (Clic here for more details about this article) |
7/44. Unusual presentation of carcinomatous meningitis: case report and review of typical CSF findings.This paper describes a previously unreported clinical onset of carcinomatous meningitis with bilateral deafness. Typical changes in the cerebrospinal fluid aside from positive cytology findings are reviewed. In cases of suspected carcinomatous meningitis the clustering of increased CSF protein, lactate, decreased glucose, and a high opening pressure is suggestive of the diagnosis.- - - - - - - - - - ranking = 0.66666666666667keywords = meningitis (Clic here for more details about this article) |
8/44. Sensorineural hearing loss associated with intrathecal vancomycin.OBJECTIVE: To report a case of nonreversible bilateral sensorineural hearing loss resulting from administration of intrathecal vancomycin. CASE SUMMARY: A 63-year-old white man with newly diagnosed pre-B-cell acute lymphocytic leukemia developed corynebacterium jeikeium meningitis associated with an Ommaya reservoir. The patient was treated with intravenous vancomycin for several days without symptomatic improvement, and intrathecal vancomycin was added to the treatment regimen. Difficulty in the patient's hearing was noted after the first intrathecal dose and he experienced complete hearing loss after the second intrathecal dose. An audiogram was performed and the patient was diagnosed with cranial nerve VIII bilateral sensorineural hearing loss. The Ommaya reservoir was removed and the patient was successfully treated with linezolid. DISCUSSION: Ototoxicity with intravenous vancomycin has been documented in multiple case reports, but this adverse effect has not been reported with intrathecal vancomycin. cerebrospinal fluid vancomycin concentrations were not measured in our patient, but there was 1 documented occurrence of supratherapeutic serum vancomycin concentrations. Other drug-related causes of ototoxicity were evaluated and intrathecal vancomycin-induced ototoxicity was considered to be possible according to the Naranjo probability scale. CONCLUSIONS: The strong temporal relationship that was seen in this case suggests the possibility of an association between administration of intrathecal vancomycin and hearing loss. Healthcare providers should consider the potential for this adverse reaction with the intrathecal route of vancomycin administration.- - - - - - - - - - ranking = 0.11111111111111keywords = meningitis (Clic here for more details about this article) |
9/44. Enteroviruses and sudden deafness.A young, healthy man presented with sudden severe sensorineural hearing loss and tinnitus. The results of the workup and neuroimaging were normal, as were the auditory brain stem responses. methylprednisolone pulse therapy was associated with significant hearing improvement within 10 days. A history of a short self-limited febrile illness preceding admission (with headache, photophobia, myalgia and fatigue), a raised serum c-reactive protein level and transient leukopenia suggested an infectious cause. Lumbar puncture revealed a mononuclear pleocytosis of the cerebrospinal fluid, with negative cultures but positive polymerase chain reaction test results for enterovirus, which was later cultured from the patient's stool. The patient's wife and baby had had a similar febrile illness without hearing loss 10 days earlier, and an outbreak of enterovirus meningitis was identified in the area, which was associated with familial clustering and echovirus serotype 4 infection. The varied causes of sudden sensorineural hearing loss, which should include enterovirus, are reviewed here.- - - - - - - - - - ranking = 0.11111111111111keywords = meningitis (Clic here for more details about this article) |
10/44. Isolated vestibular ossification after meningitis associated with sensorineural hearing loss.OBJECTIVE: Sensorineural hearing loss after bacterial meningitis is common. It is thought to be secondary to cochlear inflammation from direct bacterial seeding through the cochlear aqueduct. Although cochlear ossification with or without vestibular involvement is common, isolated vestibular ossification is rare. We review our recent experience with isolated vestibular ossification associated with profound sensorineural hearing loss and the implication for cochlear implantation in this population. STUDY DESIGN: Retrospective case review. SETTING: Academic tertiary referral center. patients: patients referred with profound sensorineural hearing loss after bacterial meningitis with evidence of ossified vestibular labyrinth but normal cochleae on computed tomographic scanning were included in the study.INTERVENTIONS We review the history, imaging findings, operative intervention, and operative findings in this series of patients.MAIN OUTCOME MEASURES Clinical history, imaging findings, operative intervention, and operative findings. RESULTS: Three patients with isolated vestibular ossification without computed tomographic evidence of cochlear osteoneogenesis were identified. Two of these patients subsequently underwent cochlear implantation with the Clarion device with complete insertion of the electrode array. Intraoperatively, one patient had isolated scala tympani ossification and the implant electrode array was placed within the scala vestibuli. CONCLUSION: A pattern of sensorineural hearing loss and isolated ossification of the vestibular system without radiographic evidence of cochlear involvement may be seen after bacterial meningitis. In these patients, magnetic resonance imaging scanning should be performed, because computed tomographic scanning may not always detect cochlear ossification. cochlear implantation is feasible in these patients.- - - - - - - - - - ranking = 0.77777777777778keywords = meningitis (Clic here for more details about this article) |
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