1/23. Acute Sin Nombre hantavirus infection without pulmonary syndrome, united states.hantavirus pulmonary syndrome (HPS) occurs in most infections with sin nombre virus and other North American hantaviruses. We report five cases of acute hantavirus infection that did not fit the HPS case definition. The patients had characteristic prodromal symptoms without severe pulmonary involvement. These cases suggest that surveillance for HPS may need to be expanded.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
2/23. Acute infection with Sin Nombre hantavirus without pulmonary edema.Acute infection with sin nombre virus has been associated with development of hantavirus cardiopulmonary syndrome (HCPS), a severe cardiopulmonary illness with respiratory failure and shock. We present two cases of Sin Nombre hantavirus infections that did not lead to marked pulmonary complications in two otherwise healthy young adults from utah and california. sin nombre virus causes a wider spectrum of disease severity than has been previously reported.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
3/23. Chronic renal failure after puumala virus infection.Chronic renal failure has never been described after Puumala hantavirus infection, which usually causes acute renal failure with spontaneous full recovery. We report a 15-year-old boy who presented with Puumala hantavirus infection and initial severe acute renal failure. His renal function gradually improved, but more than 2 years after the acute episode it was still moderately impaired, with a creatinine clearance of about 60 ml/min per 1.73 m(2)- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
4/23. The incubation period of hantavirus pulmonary syndrome.In 1993 sin nombre virus was recognized as the cause of hantavirus pulmonary syndrome (HPS) and the deer mouse (peromyscus maniculatus) was identified as the reservoir host. Surveillance by the Centers for disease Control and Prevention and state health departments includes investigation to determine the likely site(s) and activities that led to infection, an environmental assessment of the home and workplace, and possibly rodent trappings at these sites. As of December 31, 1998, there were 200 confirmed cases from 30 states (43% case-fatality ratio). The national HPS case registry was examined to determine the incubation period of HPS. review of 11 case-patients with well-defined and isolated exposure to rodents suggests that the incubation period of HPS is 9 to 33 days, with a median of 14-17 days. Case investigations allow a better understanding of the incubation time of HPS and may define high-risk behaviors that can be targeted for intervention.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
5/23. Clinical characterization of Dobrava hantavirus infections in germany.There is increasing evidence that Dobrava (DOBV) but not Hantaan (HTNV) hantavirus is a hemorrhagic fever with renal syndrome (HFRS) causing agent in Central europe. However, only single clinical cases of HFRS due to acute DOBV infection have been described so far. We report on three male patients from a non-endemic hantavirus focus in Northern germany who suffered from mild to moderate HFRS strongly resembling nephropathia epidemica. serotyping by detection of hantavirus species-specific neutralizing antibodies revealed acute infections by the HTNV-related hantavirus DOBV in all three cases. Since DOBV infections in the Balkans frequently present as severe HFRS, our cases suggest that Central-European DOBV infections have a different, less severe clinical outcome. These differences in DOBV virulence towards humans might be due to the existence of different genetic lineages of DOBV.- - - - - - - - - - ranking = 1.3333333333333keywords = infection (Clic here for more details about this article) |
6/23. Acute disseminated encephalomyelitis following nephropathia epidemica.Acute disseminated encephalomyelitis (ADEM) is an acute monophasic inflammatory and demyelinating disease of the central nervous system (CNS) occurring days to weeks after a virus infection or vaccination. Nephropathia epidemica (NE) is a haemorrhagic fever with renal syndrome caused by puumala virus, with endemic regions in europe, especially scandinavia and Western russia. We describe a case of severe nephropathia epidemica requiring dialysis, followed by severe CNS symptoms caused by ADEM. To our best knowledge this is the first case in the literature in which NE caused ADEM.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
7/23. Tula virus infection associated with fever and exanthema after a wild rodent bite.Reported here is the first case of human acute infection with Tula virus, which occurred in a 12-year-old boy in switzerland. This hantavirus had been considered apathogenic to humans, and in switzerland only TULV-genome sequences have been demonstrated in wild rodents to date. In this case, paronychia, fever and exanthema occurred after the patient was bitten by a wild rodent, indicating an unusual route of hantavirus transmission. Thus, Tula virus infection should be taken into account in patients with appropriate clinical symptoms and contact with rodents.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
8/23. hantavirus pulmonary syndrome in the State of Sao Paulo, brazil, 1993-1998.Between 1993 and 1998, 10 cases of clinical hantavirus infection were diagnosed in brazil. Hantavirus-specific IgM, or positive immunohistochemical analysis for hantavirus antigen, or positive reverse transcription-polymerase chain reaction results for hantavirus rna were used to confirm nine of these cases; eight were hantavirus pulmonary syndrome (HPS), and one was mild hantavirus disease. The remaining clinical case of hantavirus infection was fatal, and no tissue was available to confirm the diagnosis. During the first 7 months of 1998, five fatal HPS cases caused by a Sin Nombre-like virus were reported from three different regions in the State of Sao Paulo, brazil: two in March (Presidente Prudente Region), two in May (Ribeirao Preto Region), and one in July (Itapecerica da Serra Region). Epidemiologic, ecologic, and serologic surveys were conducted among case contacts, area residents, and captured rodents in five locations within the State of Sao Paulo in June of 1998. Six (4.8%) of 125 case contacts and six (5.2%) of 116 area residents had IgG antibody to sin nombre virus (SNV) antigen. No case contacts had a history of HPS-compatible illness, and only one area resident reported a previous acute respiratory illness. A total of 403 rodents were captured during 9 nights of trapping (1969 trap nights). All 27 rodents that were found to be positive for IgG antibody to SNV antigen were captured in crop border and extensively deforested agricultural areas where four of the 1998 HPS case-patients had recently worked. The IgG antibody prevalence data for rodents suggest that Bolomys lasiurus and perhaps Akodon sp. are potential hantavirus reservoirs in this state of brazil.- - - - - - - - - - ranking = 0.33333333333333keywords = infection (Clic here for more details about this article) |
9/23. Hantavirus infection in an active duty U.S. Army soldier stationed in Seoul, Korea.hemorrhagic fever with renal syndrome has been described among the U.S. and the U.N. troops assigned to the republic of korea since the korean war. However, this appears to be the first case in which infection was acquired during garrison duty in an urban environment.- - - - - - - - - - ranking = 0.83333333333333keywords = infection (Clic here for more details about this article) |
10/23. First molecular identification of human Dobrava virus infection in central europe.Viral rna was amplified by reverse transcription-PCR from a patient suffering from hemorrhagic fever with renal syndrome (HFRS) in germany. The virus strain could be assigned to the Dobrava hantavirus (DOBV). This is the first molecular identification of human infection by DOBV in central europe and the first proof that a virus strain related to the DOBV-Aa lineage, carried by Apodemus agrarius rodents, is able to cause HFRS.- - - - - - - - - - ranking = 0.83333333333333keywords = infection (Clic here for more details about this article) |
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