Cases reported "Hantavirus Infections"

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1/17. Pronounced monocytosis in a case of nephropathia epidemica.

    Nephropathia epidemica is a mild form of haemorrhagic fever with renal syndrome. thrombocytopenia is common and characteristic. We report here a case of a young man with nephropathia epidemica and marked transient monocytosis.
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keywords = haemorrhagic fever, fever
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2/17. Clinical characterization of Dobrava hantavirus infections in germany.

    There is increasing evidence that Dobrava (DOBV) but not Hantaan (HTNV) hantavirus is a hemorrhagic fever with renal syndrome (HFRS) causing agent in Central europe. However, only single clinical cases of HFRS due to acute DOBV infection have been described so far. We report on three male patients from a non-endemic hantavirus focus in Northern germany who suffered from mild to moderate HFRS strongly resembling nephropathia epidemica. serotyping by detection of hantavirus species-specific neutralizing antibodies revealed acute infections by the HTNV-related hantavirus DOBV in all three cases. Since DOBV infections in the Balkans frequently present as severe HFRS, our cases suggest that Central-European DOBV infections have a different, less severe clinical outcome. These differences in DOBV virulence towards humans might be due to the existence of different genetic lineages of DOBV.
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ranking = 9.9799998841476E-5
keywords = fever
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3/17. Acute disseminated encephalomyelitis following nephropathia epidemica.

    Acute disseminated encephalomyelitis (ADEM) is an acute monophasic inflammatory and demyelinating disease of the central nervous system (CNS) occurring days to weeks after a virus infection or vaccination. Nephropathia epidemica (NE) is a haemorrhagic fever with renal syndrome caused by puumala virus, with endemic regions in europe, especially scandinavia and Western russia. We describe a case of severe nephropathia epidemica requiring dialysis, followed by severe CNS symptoms caused by ADEM. To our best knowledge this is the first case in the literature in which NE caused ADEM.
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ranking = 1
keywords = haemorrhagic fever, fever
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4/17. Tula virus infection associated with fever and exanthema after a wild rodent bite.

    Reported here is the first case of human acute infection with Tula virus, which occurred in a 12-year-old boy in switzerland. This hantavirus had been considered apathogenic to humans, and in switzerland only TULV-genome sequences have been demonstrated in wild rodents to date. In this case, paronychia, fever and exanthema occurred after the patient was bitten by a wild rodent, indicating an unusual route of hantavirus transmission. Thus, Tula virus infection should be taken into account in patients with appropriate clinical symptoms and contact with rodents.
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ranking = 0.00049899999420738
keywords = fever
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5/17. First human isolate of Hantavirus (Andes virus) in the americas.

    We isolated Andes virus (formal name: Andes virus [ANDV], a species in the genus Hantavirus), from serum of an asymptomatic 10-year-old Chilean boy who died 6 days later of hantavirus pulmonary syndrome (HPS). The serum was obtained 12 days after his grandmother died from HPS and 2 days before he became febrile. No hantavirus immunoglobulin (Ig) G or IgM antibodies were detected in the serum sample. After three blind passages, ANDV antigens were detected in Vero E6 cells by immunofluorescence assay and enzyme-linked immunosorbent assay, and ANDV rna was detected by reverse transcription-polymerase chain reaction. A fragment of the virus genome showed 96.2% nucleotide identity with that of prototype ANDV. To our knowledge, this is the first isolation of any agent of hemorrhagic fever with HPS from a human and the first such isolation of hantavirus before symptoms of that syndrome or HPS began.
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ranking = 9.9799998841476E-5
keywords = fever
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6/17. Hantavirus infection in an active duty U.S. Army soldier stationed in Seoul, Korea.

    hemorrhagic fever with renal syndrome has been described among the U.S. and the U.N. troops assigned to the republic of korea since the korean war. However, this appears to be the first case in which infection was acquired during garrison duty in an urban environment.
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ranking = 9.9799998841476E-5
keywords = fever
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7/17. First molecular identification of human Dobrava virus infection in central europe.

    Viral rna was amplified by reverse transcription-PCR from a patient suffering from hemorrhagic fever with renal syndrome (HFRS) in germany. The virus strain could be assigned to the Dobrava hantavirus (DOBV). This is the first molecular identification of human infection by DOBV in central europe and the first proof that a virus strain related to the DOBV-Aa lineage, carried by Apodemus agrarius rodents, is able to cause HFRS.
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ranking = 9.9799998841476E-5
keywords = fever
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8/17. life-threatening Dobrava hantavirus infection with unusually extended pulmonary involvement.

    In europe, hantavirus infections usually present as hemorrhagic fever with renal syndrome and its mild form nephropathia epidemica, while clinical cases with severe pulmonary affections are extremely rare and appear to be confined to infections by New World hanta viruses in the americas. We report on a female patient from Northern germany, who suffered primarily from severe acute respiratory distress syndrome-like pulmonary failure due to Dobrava hantavirus infection that was complicated by acute renal insufficiency.
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ranking = 9.9799998841476E-5
keywords = fever
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9/17. Hantavirus Puumala infection as a cause of fever of unknown origin in a child.

    Hantavirus infection due to puumala virus causes nephropathica epidemica, a disorder characterized by fever, haematological abnormalities, mild renal dysfunction and ophthalmological abnormalities. The prevalence in most European countries is low, but the virus can be endemic. In children, hantavirus infection is rare. This paper describes a young girl diagnosed with hantavirus infection. The patient presented with high fever, proteinuria, haematuria and eye lesions, but other typical hallmarks of the disease, such as thrombocytopenia and renal dysfunction, were absent. This case report demonstrates the need to consider the diagnosis of hantavirus infection in children with prolonged fever of unknown origin. The diagnosis is based on serological tests.
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ranking = 0.00069859999189033
keywords = fever
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10/17. Hantavirus infection in thailand: first clinical case report.

    This study involved 115 cases of fever of unknown origin (FUO) patients who were admitted to the Department of medicine, Siriraj Hospital from May 1999 to November 2000. Among the patient sera screened by ELISA for IgG Hantavirus, five were positive for IgG Hantavirus-reacting antibodies and eight tested positive for IgM Hantavirus-reacting antibodies. One serum had both IgG and IgM antibodies. The patient exhibited acute encephalitic febrile illness, thrombocytopenia, high AST and ALT levels, and prolonged coagulation time. It appears that a form of the hantaan virus is circulating in thailand, which can infect humans and be pathogenic in some instances.
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ranking = 9.9799998841476E-5
keywords = fever
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