Cases reported "HIV Seropositivity"

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1/12. Incidental oral hairy leukoplakia in immunocompetent persons. A report of two cases.

    In this brief article we report on two HIV-negative patients with documented oral hairy leukoplakia who had no known risk factors for HIV infection nor any evidence of other forms of immune suppression. Therefore we conclude that in some instances hairy leukoplakia can represent an isolated and innocuous Epstein-Barr virus infection.
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2/12. Hairy leukoplakia in an HIV-negative, nonimmunosuppressed patient.

    Oral hairy leukoplakia is an Epstein-Barr virus-associated lesion that is considered to be a marker of immunosuppression. We report a case of oral hairy leukoplakia in a healthy nonimmunosuppressed elderly patient with no evidence of HIV infection on repeated investigation. This report has important implications on our understanding of the significance of this lesion.
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3/12. Hairy leukoplakia with involvement of the buccal mucosa.

    Oral hairy leukoplakia occurs mainly on the tongue of human immunodeficiency virus (HIV)-infected persons. An HIV-infected patient with hairy leukoplakia involving the tongue and buccal mucosa was studied by light and electron microscopic methods, in situ hybridization, and polymerase chain reaction. Our findings indicate that hairy leukoplakia may involve the buccal mucosa and should be considered in the differential diagnosis of white oral lesions in HIV-positive patients. Epstein-Barr virus particles were found in the epithelial cells of both buccal and tongue mucosa.
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keywords = leukoplakia
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4/12. Oral hairy leukoplakia in a HIV-negative renal graft recipient.

    Oral hairy leukoplakia (OHL) is seen almost exclusively in patients infected with HIV. A case is reported of OHL occurring in a patient who was seronegative for HIV and who had a renal graft. This occurred following an increase in his treatment with immunosuppressive drugs.
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keywords = leukoplakia
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5/12. Recurrent oral condylomata acuminata and hairy leukoplakia: an early sign of myelodysplastic syndrome in an HIV-seronegative patient.

    Oral hairy leukoplakia (OHL) has been observed in all risk groups seropositive for HIV infection. Recently, this lesion has also been described in HIV-seronegative patients with immunosuppression of iatrogenic origin. We report on a hiv-1 and hiv-2 seronegative, heterosexual man affected by refractory anemia with ringed sideroblasts (myelodysplastic syndrome), who developed recurrent oral condylomata acuminata and OHL as an early clinical manifestation. The diagnosis of OHL was confirmed by identifying Epstein-Barr viral particles by electron microscopy and by in situ dna hybridization. HIV infection was ruled out using polymerase chain reaction and testing for hiv-1 and hiv-2 antibodies.
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keywords = leukoplakia
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6/12. Multifocal hairy leukoplakia associated with Kaposi's sarcoma.

    An HIV-seropositive patient presented with multifocal lesions of both hairy leukoplakia and Kaposi's sarcoma, hairy leukoplakia being present in the epithelium covering the Kaposi's sarcoma lesions. The findings suggest that hairy leukoplakia in immunocompromised patients is both more common and more widely distributed than is generally recognised.
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keywords = leukoplakia
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7/12. Oral Kaposi's sarcoma in a woman as a first indication of HIV infection.

    Although Kaposi's sarcoma has been well described in homosexual men at risk for infection with the human immunodeficiency virus, there have been fewer reports of KS in women, and most of these have been in women who became infected with HIV through intravenous drug use. This report describes a woman who had no history of intravenous drug use in whom intraoral KS and hairy leukoplakia were the first indication of her infection with HIV.
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keywords = leukoplakia
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8/12. Oral hairy leukoplakia in an HIV-seronegative heart transplant patient.

    While oral hairy leukoplakia has been observed predominantly in patients with HIV-infection at various stages, recent reports have shown that HL may also occur in patients immunosuppressed for other reasons. This report describes oral hairy leukoplakia in a heart transplant recipient with negative HIV serology. The histopathologic diagnosis of HL was confirmed by immunohistochemical detection of EBV-VCA in the surface epithelium of the lesion and by negative staining electron microscopy.
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9/12. Oral hairy leukoplakia in an HIV-negative renal transplant patient.

    A case of oral hairy leukoplakia presenting in an HIV-negative renal transplant recipient is described. The diagnosis was confirmed by identifying Epstein-Barr viral particles in the upper prickle cell layers of the epithelium by electron microscopy and by in situ dna hybridisation.
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keywords = leukoplakia
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10/12. Oral hairy leukoplakia with extensive oral mucosal involvement. Report of two cases.

    Oral hairy leukoplakia (HL) is a lesion that occurs predominantly on the tongue in HIV-infected persons. Evidence strongly indicates that HL is related to the presence of Epstein-Barr virus in the epithelial cells. The lesion appears on the lateral border of the tongue as a painless, white plaque varying in size from a few millimeters to extensive lingual involvement. Histopathologically, the characteristic findings are hyperparakeratosis, hyperplasia, and ballooning of prickle cells resembling koilocytosis. HL is now considered a frequent, early, and specific sign of HIV infection and a strong indicator that AIDS will develop in the patient. We report on two cases of HL with marked oral mucosal involvement with extension to the pharyngeal mucosa.
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keywords = leukoplakia
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