1/13. granular cell tumor of the parotid gland. A case report.granular cell tumor (GCT), or granular cell myoblastoma, is a relatively uncommon lesion of the soft tissues. The tumor is thought to derive from a Schwann cell or from a perineural undifferentiated mesenchymal cell. GCT can occur in any organ, but the parotid gland is very unusual. A case of GCT of the parotid gland in a 30-year-old woman is described.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/13. Fine-needle aspiration cytology of primary granulosa cell tumor of the adrenal gland: a case report.Extraovarian granulosa cell tumors are extremely rare. We report on a primary granulosa cell tumor of the adrenal gland. A 69-yr-old African-American female presented with a 1-yr history of irregular uterine bleeding and a palpable right abdominal mass. CT scan showed a 9.0-cm suprarenal mass as well as an enlarged uterus. CT-guided fine-needle aspiration (FNA) cytology of the adrenal mass was interpreted as a malignant neoplasm. She underwent exploratory laparotomy, right nephrectomy, and hysterectomy with bilateral salpingo-oophorectomy. The gross, histologic, and immunohistochemical findings of the adrenal mass were characteristic of a granulosa cell tumor. The uterus contained multiple leiomyomas. The endometrium showed simple hyperplasia. Both fallopian tubes and ovaries showed no pathologic abnormality. There was no evidence of tumor elsewhere. Although rare, extraovarian granulosa cell tumor should be considered in the differential diagnosis of adrenal tumors in women showing the FNA features described herein, especially when there is evidence of excessive estrogen production. Diagn. Cytopathol. 2000;22:107-109.- - - - - - - - - - ranking = 0.83333333333333keywords = gland (Clic here for more details about this article) |
3/13. granular cell tumor of the thyroid.A case of granular cell tumor of the thyroid gland occurring in a 23-year-old woman is reported. The patient presented with a painless mass in the neck, but was otherwise in good health and had no associated disorders. Fine-needle aspiration biopsy was performed prior to surgery and yielded thyroid epithelial cells with possible oncocytic-type change. To our knowledge, the English language literature contains only one other report of a granular cell tumor of the thyroid. Our case supports the recent suggestion of a neural crest origin for some types of thyroid neoplasia.- - - - - - - - - - ranking = 0.16666666666667keywords = gland (Clic here for more details about this article) |
4/13. Congenital granular cell tumors localized to the arm.We report an instance of congenital granular cell tumors localized to the arm of a female infant. While granular cell tumors are well described during infancy as congenital epulis of the oral cavity, this case is unusual in both its location and histologic characteristics. The lesions, located around the antecubital fossa, were comprised of CD34-positive, S-100-negative granular cells. In addition, there were numerous eccrine glands in the upper dermis. The salient features of the case are discussed and reviewed in the context of the literature pertaining to this unusual entity.- - - - - - - - - - ranking = 0.16666666666667keywords = gland (Clic here for more details about this article) |
5/13. granular cell tumor of the parotid: a case report and literature review.Granular cell tumors are relatively uncommon soft tissue lesions that originate in Schwann's cells. Although these tumors can occur at any site, their presence in the parotid gland is very unusual. This article describes one such case in a 48-year-old woman, followed by a brief review of the literature on this subject.- - - - - - - - - - ranking = 0.16666666666667keywords = gland (Clic here for more details about this article) |
6/13. granular cell tumor of the parotid gland. A case report.BACKGROUND: granular cell tumor (GCT) is a relatively uncommon soft tissue tumor of putative Schwann cell origin. This tumor can occur in multiple sites as a small, nontender nodule, but the parotid gland is unusual, and only several cases have been reported. CASE: A 46-year-old woman presented with a slowly growing mass in the left preauricular region for three years. Imaging studies confirmed a nodular lesion in the superficial lobe of the left parotid gland. Fine needle aspiration (FNA) cytology revealed scattered cellular clusters and single cells with abundant granular cytoplasm and indistinct cell borders. Background exhibited eosinophilic, granular, cytoplasmic material, and some scattered naked nuclei were also noted. Histologic examination with supportive immunohistochemical and ultrastructural studies confirmed GCT. CONCLUSION: GCT of the parotid gland is very unusual. Recognition of this tumor is important to make a definitive diagnosis before an operation. FNA is useful procedure in GCT of parotid gland for a preoperative diagnosis and proper treatment.- - - - - - - - - - ranking = 1.3333333333333keywords = gland (Clic here for more details about this article) |
7/13. Symptomatic granular cell tumor of the neurohypophysis.Symptomatic granular cell tumors of the neurohypophysis or infundibulum are very rare neoplasms which are difficult to diagnose before operation. We report a case of symptomatic granular cell tumor of the neurohypophysis in a 36-year-old woman who had suffered from amenorrhea and general malaise for more than 1 year. No definite visual or neurological deficit was found. Laboratory examination revealed hyperprolactinemia and decrease of other pituitary hormones. T1-weighted magnetic resonance imaging (MRI) revealed an isointense sellar mass with suprasellar extension. Transsphenoidal subtotal tumor removal was performed and pathological examination revealed a granular cell tumor of the neurohypophysis composed of densely packed polygonal cells with abundant eosinophilic, granular cytoplasm. The granules were periodic acid-Schiff-positive and diastase-resistant. Immunohistochemical study showed positive reaction for S-100 protein and antitrypsin antibodies. Electron microscopic examination showed numerous lysosomes in the cytoplasm of tumor cells. The postoperative MRI showed the residual tumor to be just behind the pituitary stalk and that the tumor should arise from the posterior lobe of the pituitary gland. The postoperative course was smooth and there were no sequelae during 30 months of regular follow-up. We believe surgery remains the treatment of choice and even partial removal of the tumor may benefit the patient.- - - - - - - - - - ranking = 0.16666666666667keywords = gland (Clic here for more details about this article) |
8/13. Granular cell tumour of the neurohypophysis: a rare sellar tumour with specific radiological and operative features.Symptomatic granular cell tumours of the neurohypophysis are rare sellar lesions. Preoperative prediction of the diagnosis on the basis of radiological appearance is useful as these tumours carry specific surgical difficulties. This is possible when the tumour arises from the pituitary stalk, rostral to a normal pituitary gland. This has not been emphasized previously.- - - - - - - - - - ranking = 0.16666666666667keywords = gland (Clic here for more details about this article) |
9/13. granular cell tumor of penis and scrotum.Two cases of granular cell tumor of the external male genitalia are reported: one on the scrotum and one on the shaft of the penis. No previous reports of granular cell tumor of the scrotum appear in the literature. Each tumor was treated by simple excision and there was no recurrence. Each tumor showed cytoplasmic S-100 positivity. Tumor was seen in close proximity to small nerve fibers, sweat glands, and erectile smooth muscle. These findings are considered encroachments rather than evidence of origin from any of these structures. An immunohistochemical signature for granular cell tumor has developed in recent years, but, from a practical viewpoint, only the S-100 stain should be used for confirmation of the diagnosis.- - - - - - - - - - ranking = 0.16666666666667keywords = gland (Clic here for more details about this article) |
10/13. granular cell tumor of the thyroid gland in a girl receiving high-dose estrogen therapy.We describe the first case of a granular cell tumor of the thyroid. The tumor appeared while a girl was receiving high-dose estrogen therapy for tall stature. The tumor, however, did not contain estrogen or progesterone receptors. Although granular cell tumors occur twice as commonly in women as in men, the results of this case study do not provide evidence that tumor growth is mediated by direct estrogen or progesterone stimulation.- - - - - - - - - - ranking = 0.66666666666667keywords = gland (Clic here for more details about this article) |
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