Cases reported "Glioma"

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1/38. dermatofibrosarcoma protuberans in an infant with a history of choroid plexus papilloma.

    We describe an infant with a dermatofibrosarcoma protuberans (DFSP) who also had a choroid plexus papilloma. This report underscores the occurrence of DFSP in this age group and may support a neural pathogenesis of this tumor.
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2/38. Gross total removal of gliomas in the pulvinar and correlative microsurgical anatomy.

    Tumors in the pulvinar tend to present as circumscribed lesions with exophytic growth into the lateral and third ventricles. These lesions may be best explored via a parietal-transcortical-transventricular approach. If the tumor extends posteriorly or inferiorly, a posterior-interhemispheric-transtentorial approach may provide a good angle of access. Gross total removal of the tumors in the pulvinar of two patients was achieved by surgical sectioning of the unilateral crus of the fornix or the splenium via a transventricular or interhemispheric approach with acceptable risk. These patients are now doing well as students about 6 years following the first operations. During tumor removal, a posterior-interhemispheric-transtentorial approach combined with above-mentioned approaches was useful for orientation of the critical structures in the posterior incisural space. knowledge of the anatomical relationships of the pulvinar to the crus of the fornix and the choroid plexus, and to the critical structures located in the posterior incisural space is extremely important for neurosurgeons.
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3/38. choroid plexus papilloma and meningioma: coincidental posterior fossa tumors: case report and review of the literature.

    OBJECTIVE: We report an unusual case of an extraventricular choroid plexus papilloma (CPP) occupying the right ventral foramen magnum and lower right cerebellopontine angle (CPA), occurring together with a petro-tentorial meningioma. The clinical presentation, preoperative imaging, differential diagnosis, surgical treatment and histologic features of the two tumors are discussed. CASE DESCRIPTION: The patient presented with a 2-month history of headache, altered facial sensation, dysphagia, and gait unsteadiness. Neurologic examination confirmed a wide-based, unsteady gait, hoarse voice, anisocoria, and partial right vocal cord paralysis. diagnostic imaging demonstrated right petro-tentorial and right ventral foramen magnum lesions, both hyperintense on contrasted images and suggestive of meningiomas. A right suboccipital craniotomy and far lateral approach was used to resect both tumors. The petro-tentorial tumor was a histologically confirmed meningioma, but the ventral foramen magnum tumor was an extraventricular CPP. CONCLUSIONS: This is a rare occurrence of concomitant meningioma and CPP. There is no known link between these two tumors. An exophytic 4th ventricular CPP must be considered in the differential diagnosis of a CPA or foramen magnum tumor.
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4/38. Intrinsic brainstem choroid plexus papilloma. Case report.

    The authors report an intrinsic brainstem lesion that was diagnosed initially as a pontine cavernoma, which finally proved to be a choroid plexus papilloma. choroid plexus papillomas are rare tumors of the central nervous system and are usually intraventricular in location. The occurrence of this tumor in an intraparenchymal location is extremely rare, and its occurrence within the brainstem is previously unreported. The authors also report a trial of chemotherapy with lomustine in the management of the residual tumor.
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5/38. choroid plexus cyst and chordoid glioma. Report of two cases.

    Several types of mass lesions may occur in the third and lateral ventricles. Typically they arise from the lining of the ventricular cavity or from contiguous structures, by extension into the ventricle. The authors describe two patients, each of whom presented with a different rare lesion of the ventricular system. The first was a 53-year-old woman with a history of hypertension who sustained a blunt traumatic injury to the occipital region and subsequently developed a progressively worsening right-sided headache. Radiological examinations over the next 2 years revealed an enlarged right lateral ventricle and, ultimately, a choroid plexus cyst in its anterior and middle third, near the foramen of Monro, which is a rare location for these lesions. The cyst was removed en bloc, and follow-up examinations showed a significant improvement in her headache and a minimal differences in size between right and left ventricles. The authors also describe a 57-year-old man with hypertension, diabetes mellitus, and an old mycardial infarct, who presented to an outside institution with a progressively worsening headache, generalized malaise, and loss of olfactory sensation. diagnostic imaging revealed a 1.5-cm oval lesion centered in the lamina terminalis region, an open craniotomy was performed, and evaluation of a biopsy sample demonstrated the mass to be a chordoid glioma of the third ventricle, a recently described glioma subtype. Two days after surgery, he suffered a left parietal stroke and an anterior mycardial infarction. After convalescing, he presented to The University of texas M. D. Anderson Cancer Center for radiotherapy and follow up; 7 months later he was readmitted complaining of headache, short-term memory loss, and worsening confusion and disorientation. neuroimaging revealed progression of the tumor (now 2 cm in diameter), which was removed by gross-total resection. His headache resolved immediately, and 2 months later his only complaint was of episodes of confusion. Three weeks later he died of a massive myocardial infarction. These two patients represent the sixth case of an adult with a choroid plexus cyst in the anterior lateral ventricle and the 19th case of an adult with a chordoid glioma of the third ventricle, respectively.
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6/38. The cytopathology of reactions to ventricular shunts.

    A common cause of malfunctioning ventricular shunts is the occlusion of either tip by a variety of normal or reactive tissues and foreign substances. A six-year-old girl with communicating hydrocephalus and a meningomyelocele, a 48-year-old man with an ependymoma and an 11-year-old boy with a pineal germinoma had multinucleated histiocytic giant cells and ependymal cells in cerebrospinal fluid obtained from their ventricular shunts. These cellular changes were interpreted as the cytologic counterpart of the foreign-body inflammatory reactions often seen histologically on occluded shunt tips. Numerous clusters of benign choroid plexus epithelium were found in an ascitic fluid from a six-year-old girl with an optic nerve glioma and a ventriculoperitoneal shunt. Such embolism of normal tissues must be distinguished from metastases from intracranial neoplasms.
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7/38. So-called nasal glioma.

    Nasal glioma is heterotopic brain tissue which usually presents as a tumor around the nose of children and infants. We have encountered two cases of nasal glioma during the past nine years at Hokkaido University Hospital. One showed a tumor in the subcutis of the nasal bridge and the other a polypoid mass arising in the soft palate. Both consisted of proliferation of fibrillary spindle cells consistent with fibrillary astrocytes divided by fibrovascular septa. This was reminiscent of "gliosis" of the central nervous system. Occasional protoplasmic astrocytes were present in both and, in addition, one case showed neuronal cells and choroid plexus. The glial nature of the lesion was confirmed by the presence of glial fibrillary acidic protein demonstrated by the immunoperoxidase method. Nasal glioma is not neoplastic contrary to its name and is considered heterotopic brain tissue which was displaced during fetal development by similar pathogenetic mechanisms of sincipital and basal encephalocele, although its communication to the brain was lost.
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8/38. magnetic resonance imaging characteristics of choroid plexus papilloma in the fourth ventricle.

    The computed tomography (CT) and magnetic resonance (MR) imaging characteristics of two cases of small choroid plexus papilloma within the fourth ventricle are reported. CT showed the tumors as high density areas with postcontrast enhancement. MR imaging showed the tumors as basically isointense areas with marked enhancement by gadolinium-diethylenetriaminepenta-acetic acid. Important MR imaging findings included clear evidence of tumor attachment to the normal choroid plexus, location in the lower part of the fourth ventricle, and separation from the fourth ventricular floor.
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9/38. cytogenetic analysis of a choroid plexus papilloma.

    We report the cytogenetic analysis of a choroid plexus papilloma, a benign tumor, with a modal number of 56 chromosomes. In our review of the few reported karyotypes of choroid plexus tumors, we found no predictive relationship between the karyotype and the pathologic diagnosis or outcome.
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10/38. Divergent differentiation in choroid plexus papilloma. An immunohistochemical study of five cases.

    Intermediate filament and S100 expression was studied in five cases of choroid plexus papilloma. All the cases showed positivity for S100 and Nimentin. Cytokeratin and glial fibrillary protein (GFAP) intermediate filaments were present in 80 pc of the cases. None of the cases expressed epithelial membrane antigen. These results confirm the divergent differentiation of choroid plexus tumours.
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