Cases reported "Genital Neoplasms, Female"

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1/14. Laser surgery in gynecology.

    More experience and time are required to determine the advantages of laser surgery in gynecology. For precision surgery through the colposcope, the carbon dioxide laser beam appears to be useful in the control of neoplastic lesions of the vaginal mucosa and possibly of the cervix uteri. Tumor volume reduction through laser vaporization, especially when a recurrent tumor is attached to the bony pelvis, is an outstanding advantage. Adhesiolysis during myomectomy and reconstructive surgery of the fallopian tubes might be facilitated by the laser beam. Laser surgery on the vulva, both colposcopically directed and grossly with the CO2 laser scalpel, might prove to be important for the treatment of various lesions. Detailed technical knowledge, rigid safety precautions, and judicious clinical considerations are essential for competent laser surgery.
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keywords = fallopian tube, tube
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2/14. Endometrioid carcinoma of the fallopian tube resembling an adnexal tumor of probable wolffian origin: a report of six cases.

    Six adenocarcinomas of the fallopian tube that resembled the female adnexal tumor of probable wolffian origin are described. The tumors, which occurred in patients from 38 to 66 (average 55) years of age, typically formed intraluminal masses. One was an incidental finding on microscopic examination. On microscopic examination, the tumors were characterized by a predominant pattern of small, closely packed cells punctured by numerous glandular spaces, which were typically small but occasionally were cystically dilated. Many of the glands contained a dense colloid-like secretion that was positive with the periodic acid-Schiff stain. Small amounts of intracellular mucin were present in all cases. In the solid areas of three cases, spindle cells that focally formed concentric whorls were present. In all cases, small numbers of tubular glands typical of endometrioid adenocarcinoma were identified. The cytologic atypia and mitotic activity of the tumors were variable, but they exceeded that usually seen in wolffian duct tumors. The evidence indicates that this neoplasm represents an unusual form of endometrioid adenocarcinoma. It is important that it is distinguished from a tumor of wolffian duct origin.
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keywords = fallopian tube, tube
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3/14. perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.

    PEComas, occasionally associated with the tuberous sclerosis complex, are defined by the presence of perivascular epithelioid cells that coexpress muscle and melanocytic markers. This family of tumors includes angiomyolipoma (AML), clear cell sugar tumor of the lung (CCST), lymphangioleiomyomatosis (LAM), and very rare tumors in other locations. Because non-AML/non-LAM PEComas are extremely rare and their natural history and prognostic features undefined, we present our experience with 26 PEComas of soft tissue and the gynecologic tract, the largest series to date. We also performed a detailed review of the literature, with special attention to features predictive of clinical behavior. All PEComas exclusive of AML and LAM were retrieved from our consultation files. immunohistochemistry for pan-cytokeratin (CK), S-100 protein, smooth muscle actins (SMA), desmin, vimentin, HMB45, Melan-A, microphthalmia transcription factor (MiTF), TFE3, CD117, and CD34 was performed. Clinical follow-up information was obtained. Fisher's exact test was performed. The median patient age was 46 years (range, 15-97 years); there was a marked female predominance (22 females, 4 males). Sites of involvement included the omentum or mesentery (6 cases), uterus (4 cases), pelvic soft tissues (3 cases), abdominal wall (2 cases), uterine cervix (2 cases), and vagina, retroperitoneum, thigh, falciform ligament, scalp, broad ligament, forearm, shoulder, and neck (1 case each). The tumors ranged from 1.6 to 29 cm in size (median, 7.8 cm). Tumors were epithelioid (N = 9), spindled (N = 7), or mixed (N = 10). Multinucleated giant cells were present in 18 cases. High nuclear grade was noted in 10 cases, high cellularity in 7 cases, necrosis in 8 cases, and vascular invasion in 3 cases. Mitotic activity was 0 to 50 mitotic figures (MF)/50 high power fields (HPF) (median, 0 MF/50 HPF) with atypical MF in 6 cases. IHC results were: SMA (20/25), desmin (8/22), HMB45 (22/24), Melan-A (13/18), MITF (9/18), S-100 protein (8/24), CK (3/23), vimentin (12/14), TFE3 (5/17), c-kit (1/20), and CD34 (0/7). Clinical follow-up (24 of 26 patients, 92%; median, 30 months; range, 10-84 months) showed 3 local recurrences and 5 distant metastases. At last available clinical follow-up, 2 patients (8%) were dead of disease, 4 patients (17%) were alive with metastatic or unresectable local disease, and 18 patients (75%) were alive with no evidence of disease. No patient in our series had a history of tuberous sclerosis complex. recurrence and/or metastasis was strongly associated tumor size > median size (8 cm), mitotic activity greater than 1/50 HPF, and necrosis. We conclude that PEComas of soft tissue and gynecologic origin may be classified as "benign," "of uncertain malignant potential," or "malignant." Small PEComas without any worrisome histologic features are most likely benign. PEComas with nuclear pleomorphism alone ("symplastic") and large PEComas without other worrisome features have uncertain malignant potential. PEComas with two or more worrisome histologic features should be considered malignant. Occasional PEComas express unusual markers, such as S-100 protein, desmin, and rarely CK. The role of TFE3 in PEComas should be further studied.
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ranking = 0.0077440920629418
keywords = tube
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4/14. Numerical chromosome abnormalities associated with early clinical stages of gynecologic tumors.

    Cytogenetic data are presented for 12 ovarian, three endometrial, and one fallopian tube tumors. In 15 of these, primary tumors were analyzed and in one ascites was studied. All specimens were obtained at the time of diagnostic surgery. trisomy for chromosome 7 was detected in three ovarian and one endometrial tumors. In one case, trisomy 7 was the sole cytogenetic abnormality detected. Three of the four patients with trisomy 7 had early stages of adenocarcinoma. The data suggest that numerical chromosome abnormalities may be common in borderline and in less aggressive gynecologic tumors.
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keywords = fallopian tube, tube
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5/14. Immature (malignant) teratoma of the fallopian tube.

    Primary immature (malignant) teratoma of the fallopian tube is an extremely rare occurrence. We report such a case, which appears to be the third reported in the literature.
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ranking = 5
keywords = fallopian tube, tube
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6/14. Primary choriocarcinoma of the fallopian tube: report of a case.

    A case of the relatively rare condition of a choriocarcinoma in the fallopian tube is presented. The patient apparently recovered completely and quantitative beta hCG assay demonstrated negative results after TAHBSO and adjuvant chemotherapy. This brings the total cases reported to 77.
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ranking = 5
keywords = fallopian tube, tube
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7/14. Unusual behavior of low-grade, low-stage transitional cell carcinoma of bladder.

    A case report of low-grade, low-stage transitional cell cancer of the bladder with isolated metastases to the uterus, fallopian tube, and ovary is presented. The pathogenesis of such unusual behavior for a local bladder malignancy is discussed along with a review of similar cases from the literature.
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ranking = 1
keywords = fallopian tube, tube
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8/14. Histogenesis of the broad ligament adrenal rest.

    broad ligament adrenal rests are well known. A case of adrenal rest external to the surface of the broad ligament and adjacent to the fallopian tube is reviewed, with specific emphasis on its histogenesis. The rest is associated with a foreign body, and it is suggested that it has arisen as a secondary development of celomic epithelial metaplasia.
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ranking = 1
keywords = fallopian tube, tube
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9/14. Percutaneous nephrostomy for ureteral obstruction in patients with gynecologic malignancy.

    Reversible ureteral obstruction is not an infrequent complication of gynecologic malignancy or its treatment. In the past, open nephrostomy has been the standard method of management in such patients. This paper discusses the nonoperative technique of percutaneous nephrostomy which allows placement of either an external nephrostomy tube or an internal ureteral stent under local anesthesia. Six illustrative cases are presented and the indications and technical aspects of the procedure are discussed.
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ranking = 0.0038720460314709
keywords = tube
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10/14. An extra-uterine pregnancy in an ectopic fallopian tube.

    A case report of an ectopic pregnancy in a non-communicating, undescended fallopian tube. A rare embryological development-failure is described, consisting of a right hemiuterus, a remotely located noncommunicating left fallopian tube and undescended left ovary associated with agenesis of the left kidney. A noncommunicating fallopian tube should be removed when recognized to prevent ectopic pregnancy.
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ranking = 7
keywords = fallopian tube, tube
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