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1/10. Gastrointestinal mucormycosis complicated by arterio-enteric fistula in a patient with non-Hodgkin's lymphoma.

    Gastrointestinal mucormycosis is a rare, often fatal, systemic infection found predominantly in immunocompromised patients. We report a case of gastrointestinal mucormycosis in a 53-year-old female with non-Hodgkin's lymphoma. Following her first course of chemotherapy, bowel obstruction developed as a result of mucormycosis. Despite treatment with antifungal therapy, she required a laparotomy owing to severe haemorrhage caused by mucormycosal invasion of her iliac artery. With continued antifungal treatment and further chemotherapy, she ultimately underwent reversal of her Hartmann's procedure and remains disease-free.
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ranking = 1
keywords = mucormycosis
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2/10. Gastrointestinal mucormycosis in a renal transplant patient.

    The clinical course and management of a rare case of gastrointestinal mucormycosis occurring in a renal transplant patient are presented. The diagnosis was made on pathological examination of surgically resected tissue from the colon, spleen and stomach. The patient did not survive the infection. To the best of our knowledge, this is the 11th reported case of gastrointestinal mucormycosis in a solid organ transplant patient. The pathophysiology, incidence and prognosis of this disease are discussed.
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ranking = 0.85714285714286
keywords = mucormycosis
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3/10. Invasive gastrointestinal zygomycosis in a liver transplant recipient: case report.

    BACKGROUND: Gastric zygomycosis is a rare but potentially lethal complication in transplant patients. Forty-two cases of gastric mucormycosis have been described in the literature, with a mortality of 98%. methods: We report of a case of gastric mucormycosis in a 45-year-old male undergoing liver transplantation for alcohol-induced cirrhosis. The diagnosis was made 20 days after transplantation in a biopsy of a bleeding gastric ulcer identified during a reoperation for a common bile duct stricture. RESULTS: After the surgical procedure and therapy with amphotericin b, the patient made a good recovery and is alive and well 2 years after transplantation. CONCLUSIONS: Gastric mucormycosis should be suspected in those patients in whom gastrointestinal symptoms such a pain or bleeding are present. Because the diagnosis is dependent on histology, the importance of biopsy cannot be underestimated. Once diagnosed, a successful outcome depends on effective treatment with amphotericin.
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ranking = 0.42857142857143
keywords = mucormycosis
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4/10. A rare cause of intestinal perforation in an extreme low birth weight infant--gastrointestinal mucormycosis: a case report.

    We report an extreme low birth weight infant with gastrointestinal mucormycosis (GM) mimicking necrotizing enterocolitis on day 15 of age. Emergency laparotomy confirmed ileal perforations. Subsequently, tissue histology confirmed GM. This is the most premature infant who survived after GM and is the third reported neonatal survivor in English literature.
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ranking = 0.71428571428571
keywords = mucormycosis
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5/10. Antemortem diagnosis of gastrointestinal mucormycosis in neonates: report of two cases and review of literature.

    Gastrointestinal mucormycosis has been reported more frequently in adults than in children. Due to high mortality diagnosis is usually made at autopsy. Only 3 cases of neonates surviving this disease have been described. We report two cases of preterm neonates presenting clinically with symptoms of necrotizing enterocolitis (NEC), but lacking radiological characteristics of NEC where histopathology confirmed the diagnosis of gastrointestinal mucormycosis involving caecum and appendix.
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ranking = 0.85714285714286
keywords = mucormycosis
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6/10. Unusual histopathology of mucormycosis in acute myelogenous leukemia.

    mucormycosis is a mycotic disease caused by certain genera of the class Zygomycetes (order mucorales). It is usually a rapidly progressive opportunistic infection characterized by vascular invasion, neutrophilic response, and intravascular thromboses. Entomophthoromycosis describes another disease caused by Zycomycetes, but of the order Entophthorales. In contrast to mucormycosis, entomophthoromycosis is not associated with underlying disease. Vascular invasion by the hyphae does not occur, and the hyphae are surrounded by eosinophilic sheathes. These sheathes are regarded as one form of the Splendore-Hoeppli phenomenon. The authors report an unusual case of mucormycosis in a severely pancytopenic patient dying of acute myelogenous leukemia. At autopsy, eosinophilic sheathes with radiating fibrils were seen about intravascular hyphae, simulating entomophthoromycosis. This pseudo-Splendore-Hoeppli phenomenon appears to be caused by adsorption of plasma and fibrin to the hyphal walls in the absence of both neutrophilic response and extensive fibrin clotting.
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ranking = 0.85714285714286
keywords = mucormycosis
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7/10. First culture-proven gastrointestinal entermophthoromycosis in the united states: a case report and review of the literature.

    The zygomycosis are fungal infections often occurring in compromised hosts. We report the first culture-proven case of a gastrointestinal infection in the united states by Basidiobolus haptosporus (ranarum). The clinical and histological features are noted in order to distinguish this infection from the more widely reported mucormycosis.
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ranking = 0.14285714285714
keywords = mucormycosis
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8/10. Gastrointestinal mucormycosis.

    mucormycosis is an acutely malignant fungal disease causing local thrombosis and infarction. Gastrointestinal infection most commonly occurs in diabetics or in the immunologically compromised. This case demonstrates the radiological appearances of the gastrointestinal lesion and prolonged survival with amphotericin-B therapy.
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ranking = 0.57142857142857
keywords = mucormycosis
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9/10. Gastrointestinal mucormycosis causing an acute abdomen in the immunocompromised pediatric patient--three cases.

    mucormycosis is an infection caused by a ubiquitous fungus in immunocompromised individuals. Typically, it invades blood vessels, producing thrombosis and tissue infarction. This infection spans all pediatric age groups and can lead to hollow viscus perforation and bowel obstruction. A 30-month old male with large cell anaplastic lymphoma had a bowel obstruction. During emergency laparotomy, an ileoileal intussusception was identified, which required resection and anastomosis. In the pathological specimen, fungi of the mucorales order were found to be associated with tissue necrosis. On the eighth day of life, a premature infant had abdominal distension secondary to bowel perforation. Partial gastric resection and multiple intestinal stomas were performed. death occurred soon after, secondary to multiorgan failure. The autopsy and surgical specimens showed widespread mucormycosis. An adolescent had meningococcemia-induced septic shock. During recovery, hemorrhagic colitis developed, which led to perforation. The subtotal colectomy specimen showed widespread mucormycosis. The laparotomy findings are typical (black necrotic tissue involving the bowel), and when seen in the immunocompromised patient, should make one suspect gastrointestinal mucormycosis. Aggressive surgical debridement of devitalized tissue augmented by intravenous antifungal medication is the mainstay of treatment.
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ranking = 1
keywords = mucormycosis
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10/10. Gastrointestinal mucormycosis mimicking ischemic colitis in a patient with systemic lupus erythematosus.

    This report describes the case of a 42-yr-old woman with systemic lupus erythematosus who presented with septic shock. Initially, a source of infection could not be found and the patient was started on stress dose corticosteroids and antibiotics. A CAT scan revealed thickened colon and endoscopy revealed possible ischemic colitis. She soon developed peritonitis, and was taken to surgery where gastrointestinal mucormycosis was found. The patient died despite amphotericin therapy.
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ranking = 0.71428571428571
keywords = mucormycosis
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