411/1768. Unguioblastoma and unguioblastic fibroma--an expanded spectrum of onychomatricoma. Onychomatricoma is a rare tumor that appears to originate from cells of the nail matrix. Three cases of onychomatricoma that met Perrin et al.'s1 histologic criteria of onychomatricoma are described. However, using a single term to classify all three tumors ignores the apparent microscopic differences that exist among them. To demonstrate better the spectrum of so-called onychomatricoma and properly acknowledge the noticeable disparity among our cases, a series of terms is proposed. This terminology is based on the histologic spectrum of epithelial-stromal ratio of stromal cellularity and of extent nuclear pleomorphism. Use of such criteria has a precedent in the classification of follicular and odontogenic fibroepithelial neoplasms. This new nomenclature includes "unguioblastoma" for tumors with a predominant epithelial component and "unguioblastic fibroma" for tumors where a cellular stroma is more prominent and characteristic. The term "atypical unguioblastic fibroma" is used to describe a third rare neoplasm, in which the cellular stroma shows nuclear pleomorphism and atypia with an increase of mitotic activity. ( info) |
412/1768. A solitary soft fibroma-like polypoid mucinosis: report of an unusual case. BACKGROUND: Cutaneous mucinosis can be a primary or secondary reaction, as seen in connective tissue diseases, lupus erythematosus, metabolic diseases, paraproteinemias, and even malignant lymphomas. OBJECTIVE: Focal cutaneous mucinosis usually arises as a result of the dysfunction of fibroblasts in a local area. It may arrive from various mechanical stimulations. methods: We presented an unusual heretofore unreported case of a polypoid mucinosis. CONCLUSION: The local mucin deposition in this patient was considered as a secondary change from frequent friction by clothes. ( info) |
413/1768. A paediatric case of a solitary fibrous tumour of the parotid gland. Solitary fibrous tumours are rare and they were first described in the pleura of the lungs. However this rare tumour is being increasingly recognised in the oro-facial region and other extra-pleural sites among adults. We present a paediatric case of a solitary fibrous tumour of the parotid gland in an 11-year-old girl who was also diagnosed as having type I neurofibromatosis. ( info) |
414/1768. Vanek's tumor (inflammatory fibroid polyp). Report of 18 cases and comparison with three cases of original Vanek's series. Eighteen cases of Vanek's tumors are presented. The patients included nine men and nine women between the ages of 45 and 93 years (mean, 66.2 years). Nine cases were clinically diagnosed as polyps of the gastric antrum, five cases as polyps of the stomach (not otherwise specified), one polyp was located in the ileum and the three remaining polyps in the small intestine (not otherwise specified). The thirteen polyps with available size information measured from 0.4 to 5 cm in the greatest diameter (mean, 2.2 cm). Immunohistochemically, the affections were positive for vimentin (18/18) and CD34 (15/18). All the cases negative for CD34 also lacked concentric onion skin-like formations of the spindle cells around glands and vessels. The different immunophenotype and absence of concentric formations could be explained by the existence of two different lesions commonly designated as Vanek's tumor (inflammatory fibroid polyp) or by the hypothesis of various evolutional stages. In the differential diagnosis, it is important to distinguish namely eosinophilic gastroenteritis, gastrointestinal stromal tumor, inflammatory pseudotumor, hemangioendothelioma, and hemangiopericytoma. In contrast to gastrointestinal stromal tumors, genetically no substitution, deletion, or insertion occurred in c-kit exon 11 in all analyzed samples. Likewise, no deletion or insertion in part of c-kit exon 9 was observed. ( info) |
415/1768. Calcifying aponeurotic fibroma: a case report and review of literature. Calcifying aponeurotic fibroma is a rare soft tissue tumor that primarily occurs in children and adolescents and has a strong predilection for the distal portion of the extremities, especially the hands and feet. This paper presents a case report of calcifying aponeurotic fibroma. ( info) |
416/1768. Successful replacement of the interventricular septum following excision of a large intramural fibroma. Successful removal of tumours of the heart involving the ventricular septum is uncommon. review shows that of thirty endocardial fibromata reported, only six involved the septum. We wish to report another case, in which a large endocardial fibroma had replaced the ventricula septum and was removed, necessitating the reconstruction of this septum. ( info) |
417/1768. Recurrent solitary fibrous tumor of the pleura with malignant transformation. Recurrent solitary fibrous tumor of the pleura with malignant progression occurs rarely. We report a case of solitary fibrous tumor of the pleura in an 85-year-old white woman that recurred 4 times during a span of 10 years and subsequently underwent malignant transformation. The accurate diagnosis of solitary fibrous tumor is aided by ancillary techniques, such as immunohistochemical staining; however, with malignant transformation, such tools may be of limited value. Long-term clinical follow-up is recommended for all patients with solitary fibrous tumor because of the potential adverse biological behavior of this tumor, which may lead to repeated recurrences and/or malignant transformation. ( info) |
418/1768. Elastofibroma dorsi: ultrasound pattern in three patients. Elastofibroma dorsi is a rare benign tumor with a prevalence in the female population. The tumor is composed of adipose and fibrous tissue. It is typically localized at the tip of the scapular and is more frequently bilateral. Even if there are only very few reports on this topic, the incidence of the tumor seems to be less rare than expected. Elastofibroma dorsi was identified in 1961 and the first study using diagnostic ultrasound technique was published in 1996, however, since then no other major work has been produced. The purpose of the paper is to present three cases of elastofibroma dorsi, all studied by ultrasound imaging, including color and power Doppler, and by fine needle aspiration biopsy. Furthermore, in one case i.v. contrast media (Levovist) was used, and in two cases a CT and MRI evaluation was also made. Surgical excision was not performed in any of the cases. The relevant follow up was performed by clinical and ultrasound tests. In all the cases the ultrasound pattern of the elastofibroma dorsi was very similar to the surrounding muscular tissue, and neither a clear cleavage surface nor a specific vascular pattern could be evidenced. The tumor was very difficult to define from the surrounding tissue, except for a more evident coarse pattern and the same happened for the CT and MR, where a layered pattern of fatty tissue was noted. In this small cohort the tumor was mainly monolateral. The ultrasound investigation, integrated with color and power Doppler permitted a correct diagnosis, which was confirmed by the fine needle biopsy. Therefore, the less expensive ultrasound diagnosis, as a major method of screening for elastofibroma dorsi, would seem to be a reasonable proposal. ( info) |
419/1768. Right atrial papillary elastoma: an uncommon location. We present a patient with a right atrial mass, which was detected by transthoracic and transesophageal echocardiography. The patient was asymptomatic on presentation. The mass was subsequently confirmed by gross and microscopic examination to be a papillary fibroelastoma. To the best of our knowledge this is only the fourth such report of this tumor in this location. ( info) |
420/1768. Recurrent peripheral odontogenic fibroma of the attached gingiva: a case report. Peripheral odontogenic fibroma is an uncommon, benign, unencapsulated, exophytic gingival mass of fibrous connective tissue covered with a surface epithelium. Odontogenic epithelium and mineralized material may be found in the mass. A case is reported of a lesion that recurred in the attached gingiva following initial excision. Differential diagnosis of exophytic gingival lesions and post-operative management are also discussed. ( info) |