Cases reported "Fever of Unknown Origin"

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1/4. Intestinal tuberculosis presenting as fever of unknown origin in a heart transplant patient.

    patients undergoing transplantation have an increased risk of developing infections such as tuberculosis, pneumocystis carinii pneumonia, candida infections or cytomegalovirus infections because of their immunosuppressive therapy with cyclosporin A, azathioprine and steroids. Mycobacterial infection is well recognized as a complication in the immunocompromised host but diagnosis and therapy are very difficult.
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keywords = bacterial infection
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2/4. fever of unknown origin in the setting of hiv infection: guidelines for a rational approach.

    fever of unknown origin constitutes a common problem in hiv-infected patients that, paradoxically, has received little attention in the literature. A review on this topic collecting data from different series showed that mycobacterial infections, particularly tuberculosis, were responsible for the fever in more than half of the patients. However, the relative frequencies of the different etiologies may vary substantially depending on the local prevalences of certain infections. With the notable exception of tuberculosis, which may develop at any stage of hiv infection, fever of unknown origin usually presents in patients with advanced disease when the CD4 cell count is below 100/microliter. In this overview we stress, from a practical point of view, some points to be considered in the evaluation of the hiv-infected patient who presents with fever of unknown origin, as well as the usefulness and yield of several diagnostic procedures.
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keywords = bacterial infection
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3/4. Recurrent purulent triaditis in a patient with congenital x-linked agammaglobulinemia.

    A patient with congenital x-linked agammaglobulinemia, who had two separate episodes of an apparent bacterial purulent hepatic triaditis in the absence of any known local predisposing factors, is presented. These episodes may reflect the increased susceptibility of an immunodeficient patient to bacterial infections. This case demonstrates the need to consider hepatic involvement in the work-up of fevers of undetermined origin in immunodeficient patients, even in the absence of any radiologic or sonographic evidence of mechanical biliary tract obstruction.
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keywords = bacterial infection
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4/4. Contribution to the problem of occurrence of tuberculosis in patients with systemic lupus erythematosus.

    The association of SLE with tuberculosis (TB) was studied in a group of 388 patients with SLE monitored between 1953-1994. TB was diagnosed in 14 patients (3.6%). The occurrence of septic fevers in SLE patients that did not respond to glucocorticoid therapy indicated the possibility of complication with TB. SLE-associated TB included miliary and far-advanced pulmonary and extrapulmonary forms. Three patients from our group died due to myco-bacterial infection and one patient died of active SLE and TB. The treatment was successful in nine patients. early diagnosis and appropriate management are mandatory in SLE associated TB, which otherwise may have a potentially fatal outcome.
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ranking = 1
keywords = bacterial infection
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