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1/22. Testicular sperm aspiration and intracytoplasmic sperm injection for persistent infection of the ejaculate.

    OBJECTIVE: To report the successful use of testicular sperm aspiration and intracytoplasmic sperm injection in the presence of an escherichia coli-infected ejaculate that previously caused repeated embryo degeneration. DESIGN: Case report. SETTING: University medical center. PATIENT(S): A 38-year-old woman who did not conceive for 6 years with repeated IVF attempts. escherichia coli was isolated from both the oocyte culture dish and her male partner's ejaculate. INTERVENTION(S): Testicular sperm aspiration and intracytoplasmic sperm injection followed by ET. MAIN OUTCOME MEASURE(S): Clinical outcome. RESULT(S): Establishment of a pregnancy delivered at term. CONCLUSION(S): patients undergoing IVF treatment who have repeated embryo degeneration caused by bacterial infection originating in the ejaculate may be treated successfully with testicular sperm aspiration and intracytoplasmic sperm injection.
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ranking = 1
keywords = bacterial infection
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2/22. The qualitative nitroblue tetrazolium (NBT) test as a means to differentiate between infection and rejection in renal transplant patients.

    In order to determine whether immunosupression depresses the response of the NBT test to bacterial infections and to note the effect of allograft rejection on this test, a prospective study was carried out on 30 renal transplant recipients. 12 of 30 renal transplant patients developed bacterial infections and in these patients NBT readings were elevated. 12 of the remianing 18 patients who developed rejection episodes showed normal NBT results. All patients were on high doses of steroids and other immunsuppressive agents. We conclude that the NBT test may be of value in diagnosing bacterial infection in the immunsuppressed allograft recipient, and may also be an useful adjunct in the differentiation between allograft infection and bacterial infection.
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ranking = 4
keywords = bacterial infection
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3/22. Evolution of acute focal bacterial nephritis into a renal abscess.

    Acute focal bacterial nephritis (AFBN) is a localized bacterial infection of the kidney presenting as an inflammatory mass without frank abscess formation, which may represent a relatively early stage of renal abscess. The pathogenesis of AFBN is thought to be hematogenous infection or ascending infection from the lower urinary tract. For the majority of children, the pathogenesis may be related to ascending infection, because pre-existing malformative uropathy, especially vesicoureteral reflux (VUR), is common in pediatric patients. Few clinical reports have demonstrated the evolution of this condition into renal abscess in children. We report a girl with AFBN associated with VUR that evolved into a renal abscess despite appropriate intravenous antibiotic therapy. We undertook serial radiological observation of its evolution. It is important to differentiate AFBN from renal abscess because the management of the two entities may be different, and follow-up studies are indispensable to determine appropriate therapy.
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ranking = 1
keywords = bacterial infection
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4/22. Case report: hepatobronchial fistula complicating amoebiasis, treated by percutaneous catheter drainage.

    We report the case of a 41-year-old man who presented with hepatic amoebiasis 18 months after visiting the far east. His progress was initially complicated by a bronchohepatic fistula which was further complicated by secondary bacterial infection. The fistula persisted and only resolved following percutaneous catheter drainage, thereby avoiding open surgery.
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ranking = 1
keywords = bacterial infection
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5/22. Bacterial infection as a presenting manifestation of visceral leishmaniasis.

    Two patients admitted to the hospital because of severe bacterial infection were diagnosed as having visceral leishmaniasis. The types of bacterial infection were perianal abscess and pneumonia; escherichia coli and streptococcus pneumoniae were isolated from exudates and blood cultures, respectively. A third patient admitted because of acute necrotizing infection of the pharynx and visceral leishmaniasis is also discussed. Cultures from this patient failed to yield pathogens. anemia, leukopenia, or thrombocytopenia was present in all patients, and bone marrow aspirate revealed the presence of Leishmania in macrophages. We conclude that in areas where leishmaniasis is endemic, early bone marrow aspirate should, in most instances, be performed in patients with bacterial infection associated with anemia, leukopenia, or thrombocytopenia if hepatomegaly and/or splenomegaly is present.
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ranking = 3
keywords = bacterial infection
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6/22. Hemophagocytic syndrome causing complete bone marrow failure. Report of an extreme case of a reactive histiocytic disorder.

    The hemophagocytic syndrome is a reactive disorder of the mononuclear phagocytic system. Most of the cases are rare complications of common infectious and neoplastic diseases, although there may be an underlying immune disorder predisposing to this syndrome. We report a case in association with immune thrombocytopenia and hemolytic anemia (Evans' syndrome). The hemophagocytic reaction appeared after a bacterial infection of the urinary tract and presented with abrupt pancytopenia and complete hemopoietic failure. We discuss the possible mechanisms of bone marrow failure related with the hemophagocytic syndrome.
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ranking = 1
keywords = bacterial infection
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7/22. Two case reports of bacterial prostatitis with a proposed treatment for aviators.

    Bacterial prostatitis is the inflammation of the prostate gland secondary to a bacterial infection, characteristically having a chronic course with sporadic acute exacerbations. While considered to be the most common cause of recurrent bacterial urinary tract infections in the middle-aged adult male, bacterial prostatitis can be difficult to manage satisfactorily, particularly from the aeromedical perspective. The recurrent infection pattern, common for chronic bacterial prostatitis, has recently been better defined with the localization of the bacterial reservoir as being within the lumen of the prostatic ducts. Capitalizing upon "passive ion trapping" of certain lipid soluble antibiotics in this "protected" site, a two-phased, nonsurgical, pharmacological treatment is proposed for aviators. Two representative cases are reported that demonstrate such management within the setting of an operational USAF flight surgeon's office.
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ranking = 1
keywords = bacterial infection
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8/22. Primary sepsis presenting as fulminant hepatic failure.

    Four patients who were referred to the liver failure Unit with an initial diagnosis of fulminant hepatic failure were found to have severe bacterial infection from a primary septic focus as the cause of their illness. Clinical and biochemical characteristics were not helpful in differentiating these patients from those with hepatic failure from other causes, and only a high degree of suspicion will prevent delay in the diagnosis of underlying sepsis and initiation of appropriate treatment. The possible mechanisms responsible for this uncommon association are discussed.
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ranking = 1
keywords = bacterial infection
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9/22. Detection of bacterial infection of the pancreatic ducts in patients with pancreatitis and pancreatic cancer during endoscopic cannulation of the pancreatic duct.

    bacterial infections of the pancreas and bacteremia may occur during episodes of pancreatitis. Detection of bacterial infections of the pancreas in the past has required laparotomy. The present study was undertaken to determine whether bacterial infection of the pancreas occurred during nonsuppurative pancreatitis. During endoscopic cannulation of the main pancreatic duct, secretin was administered intravenously and pancreatic juice aspirated from within the duct was cultured. bacterial infections were detected in 11 of 35 patients with pancreatitis and 3 of 5 with pancreatic cancer. The pancreatic juice was sterile in 25 controls. Cultures from the common bile duct in 9 controls were also sterile whereas 4 of 6 with pancreatitis showed infected bile. The infecting organisms were principally gram-negative and the infections were usually polymicrobial. Antibiotics, where used, successfully eradicated the infecting organisms but did not appear to affect the patient's clinical course.
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ranking = 6
keywords = bacterial infection
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10/22. Late sequelae of adult-onset acute bacterial nephritis.

    The late manifestations of adult-onset acute bacterial nephritis were studied in four patients from 4 months to 5.6 years following initial infection. An unusual combination of generalized (global) wasting of the kidney and focal calyceal clubbing developed within a few weeks of the acute infection. The pattern of calyceal deformity strongly suggests papillary necrosis; it may develop during the acute phase, but go unrecognized during excretory urography at that time because of impaired contrast material excretion. The combination of a small, smooth kidney and papillary necrosis previously has been associated only with the more severe forms of analgesic nephropathy. Observations in these patients indicate that the same urographic findings may also occur as a result of a single earlier episode of acute bacterial infection of the kidney.
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ranking = 1
keywords = bacterial infection
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