1/5. 'Leopard' syndrome.'Leopard' syndrome is a rare inherited disorder associated with a high prevalence of cardiac abnormalities. General anaesthesia for dental treatment in a patient who had cardiomyopathy and bizarre electrocardiographic abnormalities associated with this syndrome is described. A thorough cardiac assessment is advised in a patient with multiple lentigines, although no clinical symptoms or signs may be found. Even if no cardiac abnormality is found before it is better to re-assess the patient, since abnormalities may develop later. The assessment should be repeated if any abnormality was detected before but without clinical significance, since the disease is progressive and may progress more rapidly in some patients than in others.- - - - - - - - - - ranking = 1keywords = anaesthesia (Clic here for more details about this article) |
2/5. Renal transplantation and diabetic autonomic neuropathy.This report describes six episodes of cardiovascular collapse in the perioperative period of a young diabetic woman undergoing general anaesthesia for renal transplantation and a similar episode after a second anaesthetic. She was subsequently found to have an autonomic neuropathy. Recommendations for the management of similar patients are made.- - - - - - - - - - ranking = 1keywords = anaesthesia (Clic here for more details about this article) |
3/5. Adriamycin cardiomyopathy. fatal outcome of general anaesthesia in a child with adriamycin cardiomyopathy.The death under general anaesthesia of a child with Adriamycin cardiomyopathy is reported. The acute, subacute and chronic cardiotoxic effects of Adriamycin are discussed and the risk factors for chronic Adriamycin cardiomyopathy presented, with particular reference to cumulative dosage of Adriamycin. The insidious onset of impairment of cardiac function is stressed and suggestions for anaesthetic management outlined.- - - - - - - - - - ranking = 5keywords = anaesthesia (Clic here for more details about this article) |
4/5. Complete heart block during anaesthesia in a patient with sarcoidosis.An apparently fit young man with sarcoidosis developed complete heart block during an emergency mastoidectomy. A temporary transvenous pacemaker was inserted, but permanent pacing was required in the postoperative period. The clinical and pathological features of cardiac sarcoidosis are described; complete heart block is the commonest presentation of cardiac involvement. The role of anaesthesia as the precipitating factor in this case is discussed.- - - - - - - - - - ranking = 5keywords = anaesthesia (Clic here for more details about this article) |
5/5. Fatal myocardial disease associated with industrial exposure to cobalt.A man of 48 went into cardiac shock under anaesthesia during an operation for a duodenal ulcer. At necropsy he was found to have changes resembling those seen in cobalt cardiomyopathy and his myocardial cobalt level was grossly abnormal. Subsequent investigations established that he had been exposed to cobalt in his work which involved handling the powdered metal. The dangers of cobalt as an industrial hazard are pointed out and it is suggested that cobalt cardiomyopathy should be considered in the differential diagnosis of cardiac disease in those employed in the hard metal industry.- - - - - - - - - - ranking = 1keywords = anaesthesia (Clic here for more details about this article) |