Cases reported "Carcinoma, Lobular"

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1/2. low back pain in a pregnant woman.

    low back pain is very common and often considered a part of normal pregnancy. Because the pain is always attributed to pregnancy, referral to a specialist is often delayed. We describe a young woman who developed low back pain and signs of progressive spinal cord compression at 33 weeks' gestation of her second pregnancy. magnetic resonance imaging of the thoracic spine showed a collapsed T11 vertebral body and a large paraspinal and intraspinal tumor compressing on the spinal cord from the right. Emergent surgical decompression and removal of the tumor mass was done. Pathological examination revealed metastatic adenocarcinoma and subsequently, a palpable nodule was found in the left breast, which, on biopsy, proved to be an invasive lobular carcinoma.
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2/2. Massive metastases from a lobular breast carcinoma from an unknown primary during pregnancy. A case report.

    BACKGROUND: Carcinoma of the breast during pregnancy represents 2-5% of all breast cancers. The frequency and histopathologic spectrum of breast cancer are similar in pregnant and nonpregnant women. Infiltrating lobular carcinoma is one of the less understood types of breast cancer, and its metastatic pattern seems to be different from that of infiltrating ductal carcinoma. breast neoplasms rarely present as cancer from an unknown primary site. CASE: A woman in the third trimester of pregnancy developed carcinoma massively metastatic to the bone marrow and liver from an unknown primary tumor. At 32 weeks' gestation a healthy male was delivered by cesarean section. The patient died 12 hours after delivery. The autopsy revealed an infiltrating lobular carcinoma, 1.5 cm, of the breast. CONCLUSION: Massive metastases from an occult lobular breast carcinoma in a pregnant woman are very rare. Diffuse metastatic spread, which often complicates or delays the diagnosis, is a characteristic pattern of infiltrating lobular carcinoma. Cancer from an unknown primary site during pregnancy is an exceptional finding. If a metastatic adenocarcinoma is diagnosed in a pregnant woman, a breast primary should be strongly suspected.
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