1/3. Intramural hematoma of the esophagus: a complication of carbon tetrachloride intoxication with acute renal failure.Following a period of prolonged severe vomiting, an intramural esophageal hematoma could be demonstrated by endoscopy and by X-ray in a 21 year old patient with hepatic and renal failure after exposure to carbon tetrachloride. The hematoma resolved spontaneously. The intramural hematoma is thought to have developed from a microdissection of the esophageal wall in the presence of a hemorrhagic diathesis.- - - - - - - - - - ranking = 1keywords = intoxication (Clic here for more details about this article) |
2/3. Quantitative assessment of carbon tetrachloride levels in human blood by head-space gas chromatography: application in a case of suicidal carbon tetrachloride intoxication.A head-space gas chromatographic method for the determination of carbon tetrachloride in human blood is described. Standard samples with 0.5 ml whole blood containing different concentrations of CCl4 were analyzed at column temperatures ranging from 50 degrees to 90 degrees C. Advantages of this method include high sensitivity, simplicity in handling, rapid achievement of reliable results, accuracy and low costs. The practicability of this analytical method was studied in a patient following suicidal oral ingestion of a lethal dose of carbon tetrachloride.- - - - - - - - - - ranking = 1keywords = intoxication (Clic here for more details about this article) |
3/3. Recurrent liver failure with severe rhabdomyolysis after liver transplantation for carbon tetrachloride intoxication.Acute liver failure due to intoxication is a rare indication for liver transplantation which a usually has a good prognosis. We herein report the case of a young male, who underwent orthotopic liver transplantation for acute liver failure due to carbon tetrachloride intoxication. Apart from hepatic and renal failure, the patient also developed severe rhabdomyolysis, which has not thus far been described as a toxic effect of this chemical agent. Despite forced hyperventilation, which is known to be the most effective means of eliminating the specifically lipophylic agent, as well as excessive plasma exchange following intravenous administration of fat emulsions, liver failure recurred when blood carbon tetrachloride concentrations were already at non-toxic levels. Retransplantation of the liver together with a kidney was only temporarily successful, since the patient died due to aspergillus sepsis. Based on this experience, we would recommend that whenever possible in patients with carbon tetrachloride intoxication, liver transplant should be delayed until most of the toxic agent has been eliminated in order to prevent fatal graft damage.- - - - - - - - - - ranking = 1.75keywords = intoxication (Clic here for more details about this article) |