1/7. Proliferative verrucous leukoplakia: report of two cases and a discussion of clinicopathology.Proliferative verrucous leukoplakia (PVL) is a recently delineated but poorly recognized form of multifocal leukoplakia that is premalignant and of unproven origin. PVL generally presents as a simple benign form of hyperkeratosis that tends to spread and become diffuse. Although slow-growing, the disease is persistent and irreversible. Clinically, PVL often presents as an exophytic wart-like form of leukoplakia that appears to be resistant to nearly all forms of therapy. PVL of the oral cavity is best-defined as a continuum of oral epithelial disease with hyperkeratosis at one end of a clinical and microscopic spectrum and verrucous carcinoma or squamous cell carcinoma at the other. The microscopic findings associated with PVL are dependent on the stage of the disease and the adequacy of the biopsy. Microscopic findings can be markedly variable. PVL is a clinicopathologic disorder that includes the microscopic entity known as verrucous hyperplasia as a component of its histopathologic progression. This article reports on two cases of PVL, describes the clinicopathology of the disease process, and presents therapeutic and etiologic considerations.- - - - - - - - - - ranking = 1keywords = leukoplakia (Clic here for more details about this article) |
2/7. Case report on a rare lesion in an hiv-infected child: hairy leukoplakia.This report describes a case of hairy leukoplakia in an hiv-infected child, and the treatment adopted. It was diagnosed by clinical and laboratory examinations, using exfoliative cytology (staining by the Papanicolaou method) and additional information was obtained by optical microscope analysis. In view of the lack of painful symptoms, of the innocuous nature of the lesion and large amount of medicines used by the patient, we decided to preserve and monitor the lesion.- - - - - - - - - - ranking = 0.71428571428571keywords = leukoplakia (Clic here for more details about this article) |
3/7. Oral hairy leukoplakia in an hiv-seronegative heart transplant patient.While oral hairy leukoplakia has been observed predominantly in patients with hiv-infection at various stages, recent reports have shown that HL may also occur in patients immunosuppressed for other reasons. This report describes oral hairy leukoplakia in a heart transplant recipient with negative hiv serology. The histopathologic diagnosis of HL was confirmed by immunohistochemical detection of EBV-VCA in the surface epithelium of the lesion and by negative staining electron microscopy.- - - - - - - - - - ranking = 0.85714285714286keywords = leukoplakia (Clic here for more details about this article) |
4/7. Treatment of candidal leukoplakia with fluconazole.A case of candidal leukoplakia (chronic hyperplastic candidosis) treated with the systemic antifungal agent, fluconazole, is reported. Dramatic clinical and histopathological resolution of the condition occurred following 11 days of drug therapy.- - - - - - - - - - ranking = 0.71428571428571keywords = leukoplakia (Clic here for more details about this article) |
5/7. Treatment of oral candida mucositis infections.Infections due to candida spp. are increasing in incidence as the number of immune compromised patients increases. The common presentation of candida mucositis and oral infections includes atrophic candidiasis, angular cheilitis, leukoplakia and oesophagitis. An increasing spectrum of antifungal agents, including imidazoles, are available for treatment and suppression of this common infection. In chronically immune-compromised patients such as those with severe hiv related immune deficiency, eradication of the infection may not be possible. This requires a stepwise approach to management and may require the use of potent, toxic agents such as amphotericin b to suppress the symptoms and signs of infection sufficiently to provide the patient with symptomatic relief. Resistant organisms are also becoming a greater problem in this patient population.- - - - - - - - - - ranking = 0.14285714285714keywords = leukoplakia (Clic here for more details about this article) |
6/7. Oral secondary syphilis in a patient with human immunodeficiency virus infection.This report describes a case of secondary syphilis in a patient with the human immunodeficiency virus (hiv) in whom the main clinical presentation of the disease was an extensive oral lesion. Few reports in the literature have focused on oral manifestations of syphilis in hiv-infected patients; most of these reports have dealt with a rare manifestation of secondary syphilis, the ulceronodular variety or lues maligna. However, in the case reported here the lesions were painless, smooth, white, oral plaques and papules on an erythematous base with a serpentine and reddish outline corresponding to the description of mucous patches. The differential diagnosis of this lesion may include oral squamous carcinoma, leukoplakia, erythroleukoplakia, candidosis, lichen planus, and granulomatous diseases. This case report emphasizes the importance of considering secondary syphilis in the differential diagnosis of oral lesions in hiv-infected patients, reinforces the importance of follow-up on the patient, and highlights the consideration for routine serologic testing for syphilis in all hiv-infected patients.- - - - - - - - - - ranking = 0.28571428571429keywords = leukoplakia (Clic here for more details about this article) |
7/7. Oral hairy leukoplakia in an hiv-negative patient with systemic lupus erythematosus.Oral hairy leukoplakia (OHL) has been reported primarily in association with hiv infection. Recently, cases have been reported in hiv-negative immunosuppressed and in immunocompetent patients. This article reports the case of an occurrence of OHL in an hiv-negative immunosuppressed patient with systemic lupus erythematosus. The case presented illustrates the importance of a thorough examination of the oral tissues in patients who are undergoing immunosuppressive therapy.- - - - - - - - - - ranking = 0.71428571428571keywords = leukoplakia (Clic here for more details about this article) |