1/10. methanol intoxication with bilateral basal ganglia infarct.methanol is a toxic agent that affects the central nervous system, especially the optic nerves and basal ganglia. Symmetrical hypodense lesions in the basal ganglia, which can be demonstrated by CT or MRI, is accepted as the most characteristic radiological feature of the disease. A case of a patient with bilateral putaminal hypodense infarcts due to methanol intoxication is presented.- - - - - - - - - - ranking = 1keywords = intoxication (Clic here for more details about this article) |
2/10. Extra-pyramidal parkinsonism complicating organophosphate insecticide poisoning.We present a 1 7-year-old female with acute extra-pyramidal parkinsonism complicating a suicidal attempt with the organophosphate insecticide chlorpyrifos, who was initially suspected to have developed severe depression or psychosis. On admission she was stupurous, with diarrhoea and massive salivation lapsing into respiratory failure and coma. Following atropine and toxogonin treatment along with mechanical ventilation she developed overt extrapyramidal parkinsonism and encephalopathy, characterized by impaired sensorium and agitation, mask facies along with a muffled voice and swallowing impairment, a resting tremor with cogwheel rigidity switching to bradykinetic choreoathetotic movements. Once a parkinsonian syndrome was diagnosed, she was given amantadine therapy with complete recovery. The patient is presently maintained on amantadine therapy; there was mild worsening of her extrapyramidal signs following unplanned discontinuation of this medication, and on follow-up assessments after 9 months she is virtually asymptomatic. A parkinsonian extrapyramidal syndrome, complicating organophosphate intoxication, should therefore also be taken into account in any patient with organophosphate poisoning, presenting with marked behavioural alterations, rigidity or akinetic mutism, and beneficial response to amantadine.- - - - - - - - - - ranking = 0.2keywords = intoxication (Clic here for more details about this article) |
3/10. A case of adult onset tic disorder following carbon monoxide intoxication.BACKGROUND: adult onset tic disorders are usually secondary in origin. We report a case of adult onset tic disorder following carbon monoxide (CO) intoxication with typical magnetic resonance imaging features. CASE REPORT: A 36-year-old woman developed temporarily suppressible patterned movements on her face, neck, and shoulder associated with sensory discomfort after CO poisoning. Magnetic resonance images showed bilateral symmetric cavitary changes in the globus pallidus. clonazepam relieved much of her symptoms. CONCLUSION: Our patient developed a monosymptomatic tic disorder following CO intoxication. This further supports that altered outflow signals from the basal ganglia, especially the globus pallidus, may contribute to the development of tic disorders.- - - - - - - - - - ranking = 1.2keywords = intoxication (Clic here for more details about this article) |
4/10. Organic schizophrenic syndrome associated with symmetrical basal ganglia sclerosis and XO/XY-mosaic.Psychopathological alterations associated with symmetrical basal ganglia sclerosis have been well characterized. A preponderance of a so-called organic affective syndrome has been reported (Konig 1989), but schizophrenic syndromes have also been described, in particular in young patients (Cummings et al 1983). Symmetrical basal ganglia sclerosis may be secondary to ischemia, hypoxia, trauma, intoxications, inflammations, or hyporesp. pseudohypoparathyroidism. Among idiopathic forms sporadic as well as familial ones with dominant and recessive inheritance have been observed (Billard et al 1989).- - - - - - - - - - ranking = 0.2keywords = intoxication (Clic here for more details about this article) |
5/10. delirium and extrapyramidal symptoms due to a lithium-olanzapine combination therapy: a case report.We report an elderly patient who developed severe delirium and extrapyramidal signs after initiation of lithium-olanzapine combination. On hospital admission, serum levels of lithium were found to be 3.0 mM/L which were far above toxic level. Immediate discontinuation of both drugs resulted in complete resolution of most of the symptoms except for perioral dyskinesia which persisted for three more months. We critically discussed the differential diagnosis of lithium intoxication and assessed confounding factors which induce delirium and extrapyramidal signs related with combination therapy of lithium and olanzapine.- - - - - - - - - - ranking = 0.2keywords = intoxication (Clic here for more details about this article) |
6/10. Extrapyramidal disturbances after cyanide poisoning (first MRT-investigation of the brain).A 29 year old student of chemistry took 50 ml of a 1% potassium cyanide solution (500 mg) in attempted suicide. He became comatose, mydriatic and was admitted to hospital in an apneic state. He woke up after seven hours and developed Parkinsonism in the following weeks. This regressed slowly in the second month after the poisoning apart from dysarthria, bradykinesia of the upper limbs and very brisk monosynaptic reflexes. Three weeks after the intoxication, CCT was largely normal, and there was CSF-dense hypodensity in both putamina after five months. Sharply delimited signal elevation in T2 corresponding to the two putamina was detected in the MRI eight weeks and five months after ingestion of the poison.- - - - - - - - - - ranking = 0.2keywords = intoxication (Clic here for more details about this article) |
7/10. Oculogyric crisis induced by lithium carbonate.A man with typical symptoms of lithium intoxication had, in addition, severe and persistent oculogyric crises, which cleared completely during recovery. Previous reports have demonstrated that lithium may impair basal ganglia activity, but this is the first reported case of oculogyric crises induced by lithium carbonate intoxication.- - - - - - - - - - ranking = 0.4keywords = intoxication (Clic here for more details about this article) |
8/10. optic atrophy and cerebral infarcts caused by methanol intoxication: MRI.We present the MRI findings of cerebral and optic pathway damage in the acute and subacute stages of methanol intoxication. In the acute stage, CT and MRI showed bilateral haemorrhagic necrosis of the corpus striatum and infarcts in the anterior and middle cerebral arterial territories. MRI in the subacute stage demonstrated atrophy of the optic chiasm and prechiasmatic optic nerves in addition to the cerebral infarcts. The patient survived, with total blindness.- - - - - - - - - - ranking = 1keywords = intoxication (Clic here for more details about this article) |
9/10. Parkinsonism after acute cadmium poisoning.A 64-year-old man suffered from acute exposure to cadmium, followed by multiple organ failure. Three months after exposure, the patient developed parkinsonian features. The case suggests that cadmium intoxication may damage the basal ganglia, resulting in parkinsonism.- - - - - - - - - - ranking = 0.2keywords = intoxication (Clic here for more details about this article) |
10/10. Anticholinergic exacerbation of phenothiazine-induced extrapyramidal syndrome.The authors used tremography to record the bilateral digital tremor of a patient showing extrapyramidal system effects in response to withdrawal from phenothiazines. They found that changes in the amplitude of tremor correlated with clinical ratings of extrapyramidal disturbance. Changes in the amplitude and in the spectrum of tremor were similar to the bipolar paradoxical changes seen during intoxication with an anticholinergic psychotogen.- - - - - - - - - - ranking = 0.2keywords = intoxication (Clic here for more details about this article) |
| | Next -> |