1/6. arsenic poisoning in a family.A family of six members is reported, who accidently consumed arsenic, during preparation of indigenous medicine in their home, and developed arsenic poisoning.- - - - - - - - - - ranking = 1keywords = family, member (Clic here for more details about this article) |
2/6. Increased neurotoxicity of arsenic in methylenetetrahydrofolate reductase deficiency.A 16-year-old girl from Surinam presented with mental deterioration and severe paraparesis with areflexia and bilateral Babinski signs. Laboratory examination showed a hyperhomocysteinemia that was caused by 5,10-methylene-tetrahydrofolate reductase (MTHFR) deficiency. In addition, urine samples contained large amounts of arsenic. An open bag with the pesticide copper acetate arsenite was found to be the source of exposure. In remethylation defects such as MTHFR deficiency, the concentration of methyldonors is severely reduced. As arsenic is detoxified by methylation, we suggest that the MTHFR deficiency in this girl might explain the fact that of all family members exposed to arsenic, only she developed severe clinical signs and symptoms of arsenic poisoning.- - - - - - - - - - ranking = 0.22531416060052keywords = family, member (Clic here for more details about this article) |
3/6. Arsenic in a child's world.Ten-year-old Tim P. presented at a local emergency room complaining of bloody diarrhea. Despite treatment, his diarrhea continued with additional symptoms of nausea, raspy voice, headaches, abdominal pain, tingling of the feet and hands, lethargy, and eczema. Do you recognize the health risks and clinical aspects of arsenic, and could you assist Tim and his family?- - - - - - - - - - ranking = 0.19367145984987keywords = family (Clic here for more details about this article) |
4/6. Persistent neuropathy and hyperkeratosis from distant arsenic exposure.The purpose of this case series is to assess long-term sequelae of arsenic exposure in a cohort acutely exposed to arsenic in drinking water from a well dug into a landfill containing arsenical pesticides. Ten of the 13 individuals (or next of kin) in the initial study agreed to participate in the follow-up study. Next of kin provided questionnaire data and released medical information on the three individuals who had died. The remaining seven cohort members were assessed by an interview, questionnaire, detailed physical examination and sensory nerve testing. Available medical records were obtained and reviewed. Sensory testing was performed using an automated electrodiagnostic sensory Nerve Conduction Threshold (sNCT) evaluation. Sensory complaints and electrodiagnostic findings consistent with polyneuropathy were found in a minority (3/7) of subjects 28 years after an acute toxic arsenic exposure. Two of the seven patients examined (1 of 3 with neuropathic findings) also had hyperkeratotic lesions consistent with arsenic toxicity and one of the patients had hyperpigmentation on their lower extremities possibly consistent with arsenic toxicity.- - - - - - - - - - ranking = 0.031642700750648keywords = member (Clic here for more details about this article) |
5/6. Atempted homicide with arsenic.An unusual method of introducing arsenic to water with homicidal intentions, where five members of the same family were poisoned, is reported. The obvious initial diagnosis of food poisoning or food allergy was reviewed when the story of noticing an unusual substance in the well was revealed. The patients recovered fully after conventional intramuscular dimercaprol.- - - - - - - - - - ranking = 0.22531416060052keywords = family, member (Clic here for more details about this article) |
6/6. Seasonal arsenic exposure from burning chromium-copper-arsenate-treated wood.All eight members of a rural wisconsin family experienced recurring neurological and medical illness over three years, especially during the winter months. Arsenic, in concentrations of 12 to 87 ppm, was noted in the hair of the mother and father, and analysis of hair and fingernails of all family members demonstrated pathological levels of arsenic. For four years the five-room home had been heated with a small wood stove in which outdoor or marine plywood and wood remnants had been preferentially burned. Stove ashes that contained more than 1,000 ppm of arsenic contaminated the living area, and the ratio of copper, chromium, and arsenic pentoxide in this ash matched the ratio used in the chromium-copper-arsenate-treated wood.- - - - - - - - - - ranking = 0.45062832120104keywords = family, member (Clic here for more details about this article) |