1/48. Perianal cytomegalovirus ulcer in an hiv infected patient: case report and review of literature.We report the case of a 25-year-old man with acquired immunodeficiency syndrome, presenting with perianal ulcer and diarrhea. He had positive immunocytochemical tests for cytomegalovirus (CMV) in circulating polymorphonuclear cells (PMN). The biopsy specimen was suggestive of CMV infection, and specific immunoperoxidase for CMV antigens positively stained endothelial cells and fibroblasts. In this report we review cutaneous CMV infection in immunocompromised patients.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
2/48. The clinical spectrum of clostridium sordellii bacteraemia: two case reports and a review of the literature.clostridium sordellii is rarely associated with disease in humans. Since its first report in 1922 only a few cases of bacteraemia have been reported. This report describes two cases of C sordellii bacteraemia; the oldest and youngest patients reported to date. The first, is a previously well 81 year old woman presented with perianal infection, which was later complicated by thrombosis of the aorta, and the second is a 12 year old boy with epilepsy who presented with an ear infection. These cases are also highlighted to demonstrate the wide spectrum of presentation of sordellii bacteraemia.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
3/48. Leukocyte adhesion deficiency.Leukocyte adhesion deficiency is a rare syndrome with autosomal recessive pattern of inheritance. An eleven-month-old boy, whose parents were first degree relatives, was referred to clinic with recurrent episodes of pneumonia, otitis and extensive necrotic wounds of perianal area since neonatal period. His umbilical cord had separated 30 days after birth. Laboratory findings included marked leukocytosis, chemotaxis abnormality, and very low levels of CD 11 (0.5%) and CD 18 (2%). Leukocyte Adhesion Defect (LAD) is rare genetic defect of a group of leukocyte membrane glycoproteins. LAD affects nearly one out of every million individuals and is characterized by recurrent bacterial and fungal infections of skin and mucous membranes, diminished pus formation, delayed umbilical cord separation, granulocytosis, poor wound healing and progressive periodontitis. This is the first report of a case of LAD in Isfahan of iran.- - - - - - - - - - ranking = 0.5keywords = infection (Clic here for more details about this article) |
4/48. Perianal ulceration in a "healthy" Chinese man with disseminated tuberculosis.Orificial tuberculosis (OTB) is a rare form of cutaneous mycobacterium tuberculosis infection affecting the mucosa and skin around orifices in patients with advanced internal tuberculosis and poor general health. We report a 72-year-old Chinese man who had a 10-year history of OTB with disseminated tuberculosis infection of the lungs and urinary tract. He appeared surprisingly healthy and had been free from systemic symptoms all along despite widespread tuberculosis. The diagnosis of OTB was established by the microscopic presence of acid-fast bacilli (AFB) in the tissue section and was rapidly confirmed by polymerase chain reaction (PCR) to be mycobacterium tuberculosis. PCR shortens the time of diagnosing rare presentations of cutaneous tuberculosis and prevents delays in treatment. Conventional culture is still important in confirming the diagnosis and screening for drug resistance.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
5/48. An unusual presentation of Y-type urethral duplication with perianal abscess: case report.Urethral duplications are rare anomalies that manifest in various anatomic forms. These variations are classified broadly as epispadic, hypospadic, and Y-type duplications. In the Y-type, the accessory ventral channel opens into either the perineum or the anal canal. Typically, the dorsal urethra is hypoplastic, and the external meatus is stenotic, so urine is voided through the dominant ventral channel. In the other unusual form, the dorsal urethra is normal and perineal or rectal opening of accessory ventral urethra is an accidental finding. When treating patients with typical Y-type duplications, the accessory ventral urethra is mobilized and then is carried to the glans with one- or 2-stage urethroplasty. In the unusual form, excision of the anterior urethra is the definitive surgical treatment. This report describes a case of unusual Y-type urethral duplication in which the accessory ventral channel had a stenotic perianal opening. The patient developed recurrent attacks of perianal abscess associated with urinary tract infections. To the authors' knowledge, this is the first reported case of Y-type duplication with an hypoplastic accessory ventral channel that was presented with recurrent perianal abscess attacks.- - - - - - - - - - ranking = 0.5keywords = infection (Clic here for more details about this article) |
6/48. Nodular perianal herpes simplex with prominent plasma cell infiltration.BACKGROUND: Nodules are exceptional manifestations of herpes simplex virus (HSV) infection in immunocompromised patients. Only two cases of nodular HSV-2 infection of the perianal region have been reported previously. GOAL: The case of a 46-year-old homosexual man with AIDS presenting with painful perianal nodules resembling squamous cell carcinoma is described. STUDY DESIGN: This case report presents details of the histologic findings and treatment regimen. RESULTS: Histologic examination showed the presence of rare multinucleated giant epithelial cells and a dense inflammatory infiltrate composed mostly of plasma cells. polymerase chain reaction analysis was positive for HSV-2 and negative for HSV-1, cytomegalovirus, Epstein-Barr virus, and human herpesvirus types 6 and 7. After being treated ineffectively with oral acyclovir (4 g/d) for 15 days, the patient was treated with oral valacyclovir (6 g/d), resulting in marked improvement in 10 days and complete resolution after 2 months. CONCLUSIONS: In immunocompromised patients, HSV-2 infection may present with atypical clinical and histopathological features.- - - - - - - - - - ranking = 1.5keywords = infection (Clic here for more details about this article) |
7/48. Unusual presentation of angiocentric T-cell lymphoma mimicking perianal abscess.BACKGROUND: Subcutaneous angiocentric T cell is a common form of cutaneous lymphoma localized within subcutis mimicking lobular panniculitis. It is rarely manifested as perianal skin lesion. OBJECTIVE: To suggest that perianal T-cell lymphoma is a rare entity that should be included in the differential diagnosis of perianal infiltrate mimicking perianal abscess. methods AND RESULTS: A 65-year-old woman presented with painful perianal infiltrate mimicking a perianal abscess. The pain lasted seven days and there was no evidence of fever. Bacterial examination of tissue of the infiltrate discovered staphylococcus aureus. Angiocentric T-cell lymphoma was demonstrated on biopsy. CONCLUSION: Our case represented sequela of subcutaneous angiocentric T-cell malignant lymphoma with a complication of a secondary infection mimicking perianal abscess. In patients presenting with a perianal infiltrate without abscess, a malignant condition should be considered a differential diagnosis and a biopsy should be performed.- - - - - - - - - - ranking = 0.5keywords = infection (Clic here for more details about this article) |
8/48. Persistent perianal abscess in early infancy as a presentation of autoimmune neutropenia.Autoimmune neutropenia of infancy is a primary, usually self-limiting, antineutrophil autoimmune phenomenon seen in infancy and early childhood. These infants are at a higher risk of infection, and early detection, particularly with the availability of newer therapeutic options such as hematopoietic growth factors, can allow close follow-up and, if needed, treatment. We report two infants with autoimmune neutropenia who presented with a persistent perianal abscess, which has not been documented previously in this population.- - - - - - - - - - ranking = 0.5keywords = infection (Clic here for more details about this article) |
9/48. cytomegalovirus-associated perianal ulcerations in AIDS.We report two patients with the acquired immune deficiency syndrome and cytomegalovirus associated perianal ulcerations. Both complained of chronic, painful, nonhealing ulcers that required surgical intervention for diagnosis and palliation. One patient developed diffuse cytomegalovirus infection and both had poor response to gancyclovir therapy. We review the pertinent clinical and pathologic findings of this serious manifestation of cytomegalovirus infection.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
10/48. Therapeutic regimens for anorectal gonococcal infection in males.Anorectal gonococcal infection is particularly prevalent in women and homosexual men. Although the currently recommended public health Service therapeutic regimens for uncomplicated gonorrhea appear to be effective also for anorectal gonorrhea in women, their efficacy for anorectal infection in men has not been adequately evaluated. We report a case of gonococcal proctitis in a homosexual man that did not respond to therapy with ampicillin plus probenecid and tetracycline, but subsequently responded to spectinomycin therapy. Currently available therapeutic regimens for anorectal gonococcal infection in males are reviewed.- - - - - - - - - - ranking = 3.5keywords = infection (Clic here for more details about this article) |
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