1/126. A unique case of desmoplastic ameloblastoma of the mandible: report of a case and brief review of the English language literature.A unique case of desmoplastic ameloblastoma is reported from the clinical, radiographic, and histologic viewpoints. The patient was a 56-year-old man who complained of a painless swelling on the buccal aspect of the left mandible. Periapical and panoramic radiographs revealed a rounded, slightly radiolucent area with blurred osteosclerotic margins. Occlusal radiograph and computed tomography images disclosed buccal bone expansion outlined by thinned cortices. Computed tomography images exhibited an enhanced area in the anterior portion of the lesion. Interestingly, the coronal computed tomography images revealed a close relationship between the periodontal membrane of the left mandibular second premolar and the enhanced area. biopsy specimens from the anterior portion of the lesion displayed typical histologic features of the desmoplastic variant of ameloblastoma. However, those from the posterior portion disclosed a large cystic formation. Oxytalan fibers were identified in the stromal tissue of the tumor, which suggested that the tumor arose from the epithelial rests of Malassez in the periodontal membrane of the related tooth. We also reviewed previously reported 41 cases. In 36 of 38 cases in which the location was specified, the tumor was found in the anterior to premolar region of the maxilla or mandible. A radiographic description was given in only 29 previous cases, 28 of which involved multilocular lesions. No cyst as large as the one in the present case was found among the previously reported desmoplastic ameloblastomas. Although the present case deviates from the usual desmoplastic variant of ameloblastoma in terms of locus, radiologic appearance, and cyst formation, it still meets the histologic criteria for this variant in both the stromal and epithelial components.- - - - - - - - - - ranking = 1keywords = mandible (Clic here for more details about this article) |
2/126. Giant ameloblastoma: report of an extreme case and a description of its treatment.ameloblastoma is an odontogenic tumor that usually occurs in the mandible. It is an aggressive but benign tumor of epithelial origin that is rarely metastatic. We report the case of a 53-year-old woman who had a massive ameloblastoma of the mandible. The tumor measured 15.2 x 11.4 x 12.0 cm. The patient had oral bleeding that required a transfusion. The workup included three-dimensional imaging, arteriography, and embolization to control bleeding. Surgical management entailed the resection of the entire left mandible and right symphysis, followed by reconstruction with a free fibular flap. To our knowledge, this is the largest reported ameloblastoma managed with three-dimensional imaging, radical resection, and free-flap reconstruction. This article also reviews aspects of the differential diagnosis, pathology, and management of jaw tumors.- - - - - - - - - - ranking = 0.5keywords = mandible (Clic here for more details about this article) |
3/126. So-called 'hybrid' lesion of desmoplastic and conventional ameloblastoma: report of a case and review of the literature.So-called 'hybrid' lesion of ameloblastoma, which is composed of desmoplastic ameloblastoma and conventional follicular/plexiform ameloblastoma, is an unusual variant of ameloblastoma and only eight cases of 'hybrid' lesion have been published in the English literature. To enhance knowledge of this interesting tumor, we add a case of 'hybrid' lesion that occurred in the right mandible of a 48-year-old Japanese male. Radiographic examination disclosed a honeycomb appearance at the anterior alveolar region, combined with a unicystic radiolucency in the molar region of the mandibular body. Histologically, the former showed microscopic features of desmoplastic ameloblastoma and the latter those of follicular ameloblastoma with focal granular cell transformation. The lesion was enucleated with curettage of surrounding bone and the lesional cavity was marsupialized. Although tumor tissues reappeared at 3, 5, 7 and 14 months after the surgery, the patient has remained disease free for 11 years after the last vaporization by CO2 laser of the recurred tumor. Many more cases of 'hybrid' lesion are needed to clarify the clinicopathological, histopathological and biological characteristics of this interesting variant of ameloblastoma.- - - - - - - - - - ranking = 0.16666666666667keywords = mandible (Clic here for more details about this article) |
4/126. ameloblastoma containing mucus glands.A 53-year-old woman had a large, deforming mass involving the mandible and was treated by subtotal mandibulectomy. Histologically, the mass proved to be an acanthomatous ameloblastoma that contained mucus glands. Eleven years after the mandibulectomy, the tumor has not recurred or metastasized.- - - - - - - - - - ranking = 0.16666666666667keywords = mandible (Clic here for more details about this article) |
5/126. Intraosseous squamous cell carcinoma arising in association with a squamous odontogenic tumour of the mandible.We report a rare occurrence of intraosseous squamous cell carcinoma (SCC) arising in association with a squamous odontogenic tumour (SOT), which had not previously been documented in the literature. A 53-year-old man had, for 5 years, a well-demarcated radiolucency attached to the impacted third molar of the mandible. The enucleated specimen had a characteristic pattern of SOT, but in which a few epithelial islands showed atypical features suggestive of SCC. Intense p53-, proliferating cell nuclear antigen- and Ki-67-positive cells were detected in carcinoma areas. Within 2 months, aggressive bone destruction showing typical findings of intraosseous SCC appeared. The present tumour is presumably a malignant variant of SOT.- - - - - - - - - - ranking = 0.83333333333333keywords = mandible (Clic here for more details about this article) |
6/126. Ameloblastic fibroma: report of case.A 3-year-old girl had a large, painless, radiolucent lesion that involved the right side of the mandible. The lesion extended from the canine region to the condyle and coronoid process. A microscopic diagnosis of ameloblastoma was made by the hospital pathologist. Because it is unusual to find an ameloblastoma in a 3-year-old child and because the extensive surgical procedure that would be necessary to remove an ameloblastoma of this size, further consultation was required. As a result, the lesion was diagnosed as an ameloblastic fibroma and a more conservative surgical procedure was performed. Sixteen months after surgery, radiographic evidence showed complete resolution of the bony surgical defect, with no evidence of recurrence. This case once again points out the necessity for exact diagnosis of similar histologic lesions that may require a different approach in treatment.- - - - - - - - - - ranking = 0.16666666666667keywords = mandible (Clic here for more details about this article) |
7/126. A simple prosthetic approach using cement-retained implant prosthesis after surgical treatment of ameloblastoma.ameloblastoma is an odontogenic tumor of epithelial origin that manifests itself in the maxillofacial area with marked deformity. After removal of the tumor, prosthetic reconstruction may be challenging because of extensive tissue loss, which necessitates careful treatment planning. We describe a case in which a patient lost considerable supporting tissue after excision of the tumor. The mandible was grafted with autogenous corticocancellous bone harvested from the left anterior iliac crest in a delayed manner. After healing, six implants were placed. After second-stage surgery, a new method was used to reduce thickness of the soft tissue around the implants. A cement-retained nine-unit fixed partial denture was fabricated in three clinical visits. The patient has been monitored for 5 years with no complications despite the use of cement to retain the prosthesis and the unfavorable crown-to-root ratio.- - - - - - - - - - ranking = 0.16666666666667keywords = mandible (Clic here for more details about this article) |
8/126. ameloblastoma--a diagnostic problem.A 50-year-old female was referred by her dental practitioner. She had a periapical radiolucency associated with the lower right second premolar tooth. The tooth was root treated and subsequently apicected. Tissue curetted at the time of surgery was shown to be a solid ameloblastoma which was managed initially by marginal excision. Histopathological examination of the resection specimen demonstrated tumour at the inferior margin. A segmental resection of the mandible with an immediate reconstruction using a free tissue transfer of the iliac crest was therefore performed. The case shows the need for vigilance in dealing with periapical pathology and underlines the importance of sending all tissue specimens for histopathological analysis.- - - - - - - - - - ranking = 0.16666666666667keywords = mandible (Clic here for more details about this article) |
9/126. Epidermal nevus syndrome with development of a mandibular ameloblastoma.Epidermal nevus syndrome (ENS) is a hamartoneoplastic syndrome characterized by the association of epidermal nevi with abnormalities in other organ systems. We report a 32-year-old woman with ENS that, in addition to cutaneous manifestations, showed red plaques on the maxillary and mandibular labial alveolar mucosa and a papillomatous lesion of the midline posterior hard palate. Radiographic examination of the jaws was noncontributory. Approximately 5 years later, a follicular ameloblastoma developed in the mandible. The tumor showed duct-like cystic spaces, continuity with the overlying epithelium, and globular myxomatous areas in the connective tissue. The palatal lesion was diagnosed as papilloma, whereas the maxillary plaques showed nonspecific mucositis. The association of ameloblastoma with ENS is discussed. This is the second case of ENS associated with ameloblastoma reported in the medical literature.- - - - - - - - - - ranking = 0.16666666666667keywords = mandible (Clic here for more details about this article) |
10/126. ameloblastoma of the jaws.ameloblastoma is a histologically benign tumor derived from odontogenic apparatus. The tumor can infiltrate into surrounding tissues. Although it is benign, it presents symptoms of a malignant tumor, such as infiltration into the lungs, pleura, regional and distant metastases, orbit, base of skull, brain and has resulted in death. It also has a high incidence of recurrences, the existence of regional or distant metastasis, showing a microscopic pattern of ameloblastic carcinoma with cytologic features of an increasing nuclear/cytoplastic ratio, nuclear hyperchromatism, and the presence of mitosis. We report a study of 12 patients of ameloblastoma of the jaws between January 1992 and December 1996 consisting of 8 affected in the mandible and 4 in the maxilla. One patient with a tumor in the maxilla was excluded from this study, due to a different histological and clinical behaviour of the ameloblastoma.- - - - - - - - - - ranking = 0.16666666666667keywords = mandible (Clic here for more details about this article) |
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