Cases reported "Amblyopia"

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1/6. amblyopia: the condition, the challenge and the cure.

    1. amblyopia needs to be detected early for the patient to have the greatest chance of total vision correction. 2. compliance with treatment for amblyopia, while not medically complex, may be difficult both socially and emotionally. 3. Support and education, provided by programs such as Prevent blindness America's eye Patch Club, facilitate compliance and, therefore, the cure.
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2/6. Decreased activation of the lateral geniculate nucleus in a patient with anisometropic amblyopia demonstrated by functional magnetic resonance imaging.

    Although postmortem morphological changes in the lateral geniculate nucleus (LGN) have been reported in human amblyopia, LGN function during monocular viewing by amblyopic eyes has not been documented in humans. We used functional magnetic resonance imaging (fMRI) to study monocular visual activation of the LGN in a patient with anisometropic amblyopia. Four normal subjects, a patient with optic neuritis and a patient with anisometropic amblyopia were studied with fMRI at 1.5 T during monocular checkerboard stimulation. Activated areas in the LGN and visual cortex were identified after data processing (motion correction and spatial normalization) with SPM99. In the 4 normal subjects, comparable activation of the LGN and visual cortex was obtained by stimulation of either the right or left eye. In the patient with unilateral optic neuritis, activation of the LGN and visual cortex was markedly decreased when the affected eye was stimulated. Similarly, decreased activation of the LGN as well as the visual cortex by the affected eye was demonstrated in the patient with anisometropic amblyopia. Our preliminary results suggest that activation of the LGN is diminished during monocular viewing by affected eyes in anisometropic amblyopia. fMRI appears to be a feasible method to study LGN activity in human amblyopia.
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3/6. Characteristic ocular findings in patients with craniofacial cleft.

    PURPOSE: To identify the characteristic ocular findings in patients with craniofacial cleft (CFC). methods: Ophthalmologic examination was performed for a 16-year-old girl with no. 3 CFC and a 3-year-old boy with no. 5 CFC. RESULTS: exotropia was found in the 3-year-old boy with no. 5 CFC involving the lateral orbit, and esotropia in the 16-year-old girl with craniofacial cleft no. 3 involving the medial orbit. Hypotropia, lower eyelid coloboma, amblyopia and an absence of stereopsis were common to both patients. visual acuity was improved from hand motion to 20/30 by means of occlusion therapy for amblyopia in the 3-year-old boy. strabismus surgery resulted in exophoria of 8 prism diopters (PD) in the 3-year-old boy and left esotropia of 8 PD in the 16-year-old girl. CONCLUSIONS: amblyopia, hypotropia, esotropia (no. 3) and exotropia (no. 5) should be verified in cases of CFC nos. 3 and 5. Ophthalmologic examination and early intervention for amblyopia may be mandatory for patients with CFC involving the orbit.
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4/6. Good visual outcome after endophthalmitis in an eye previously treated successfully for amblyopia.

    A child with an extensive periorbital hemangioma developed an endophthalmitis caused by staphylococcus aureus after her second strabismus surgical procedure. Treatment with vitrectomy and intraocular antibiotics and steroid resulted in preservation of her eye. Despite previous successful treatment for amblyopia in that eye, her visual acuity improved from hand motion during the acute episode of endophthalmitis to 20/40 -2.
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5/6. Some functional abnormalities in amblyopia.

    In discussing the relationship between anomalous retinal correspondence and amblyopia, it is suggested that amblyopia may be due not only to suppression and/or non-use of the deviated eye, but also to a mis-use of this eye. The interaction of the 'focal' and 'ambient' systems in amblyopia and the relationship of the 'ambient' system to the interocular transfer of the motion after-effect are discussed. This effect has been found to be of no clinical significance in predicting the presence or absence of binocular cooperation. It is concluded that in cases of amblyopia there is either no disturbance in the 'ambient' system or an adaptation of the latter to the pathological condition.
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6/6. Alcohol amblyopia.

    Alcohol amblyopia is a disorder that affects a small percentage of alcoholic patients, most of whom are nutritionally deficient. A battery of tests is required to make the diagnosis including color vision and field testing. Once the diagnosis is made, physical, emotional, and visual rehabilitation should be undertaken. A case of alcohol amblyopia is presented along with optometric management techniques.
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