1/5. Isolated gastric involvement in Crohn's disease. Report of a case simulating scirrhus carcinoma.A 63-year-old woman suffered a short period of nausea and vomiting. X-ray examination of the upper gastrointestinal tract was suspicious of scirrhus carcinoma of the stomach. At operation the suspicion was strengthened, and total gastrectomy was performed. Microscopic examination showed chronic, granulomatous gastritis compatible with Crohn's disease. The patient died on the 8th day postoperatively with caval thrombosis obliterating the inlet to the right auricle. No other localization of the disease could be demonstrated on thorough microscopic and macroscopic examination of the whole gastrointestinal tract.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |
2/5. Primary linitis plastica of the descending colon: a case report.A rare case of primary linitis plastica carcinoma of the colon seen in a 44 year old Japanese man is described herein. The patient had a complete obstruction of the descending colon and was treated with a loop colostomy followed shortly afterward by a left hemicolectomy. At the time of the second operation, the entire thickness of the colonic wall was found to be infiltrated by cancer cells, however, the other intraabdominal organs were free of cancerous involvement. The histopathological diagnosis made at this time was primary linitis plastica carcinoma of the descending colon. Nine months later, the patient developed an intestinal obstruction and relaparotomy revealed diffuse peritoneal dissemination. Two years after the first operation, upper GI films and a gastrofiberscopic examination revealed gastric involvement. The patient died 28 months after his initial operation, and autopsy revealed widespread metastases in the peritoneal surface, paraaortic lymph nodes, small intestine, remaining colon and stomach.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |
3/5. Sclerosing-sweat-duct (microcystic adnexal) carcinoma--a tumor from a single eccrine origin.A patient with a sclerosing-sweat-duct carcinoma of the upper lip is reported. Histologically the tumour showed solid islands and strands of squamous cells and sparse small ductal structures, some of them containing central cores of dense eosinophilic keratin. All this was embedded in a sclerotic stroma. These features, in addition to positive immunoreactivity for carcinoembryonic antigen (CEA) in the lumina of small ducts, and the presence of S-100 protein-positive cells in some cords and ducts, are consistent with the notion that this tumour exhibits differentiation toward eccrine sweat structures.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |
4/5. Metastatic breast carcinoma of the orbit.Two Caucasian females in whom an orbital mass was the first sign of metastasis from a breast carcinoma are described. Each subject had undergone a radical mastectomy to treat a primary breast carcinoma, one six years and the other eight years previously. Each presented with ipsilateral proptosis, and restricted upper eyelid action; one had altered ocular motility. In each subject an open biopsy of the orbital mass via an eyelid crease incision revealed metastatic scirrhous adenocarcinoma of the breast. The clinical features, investigations, and treatment of orbital metastases from breast carcinoma are discussed.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |
5/5. retroperitoneal fibrosis associated with scirrhous gastric cancer.A case of retroperitoneal fibrosis associated with scirrhous gastric cancer is reported. A sixty two-year-old Japanese female was admitted because of acute renal failure. The patient's serum creatinine level showed 3.2 mg/dl while the blood urea nitrogen level was 23 mg/dl. An ultrasound study of the upper abdomen revealed bilateral hydronephrosis. Drip infusion pyelography revealed a dilated right renal pelvis without ureteral obstruction. The left kidney was not opacified, suggesting a functional disorder. Gastrography and gastrofiberscopy revealed scirrhous gastric cancer. Signet ring cell carcinoma was later demonstrated histologically by biopsy specimens. CT demonstrated a prominent thickening of the gastric wall and hydronephrosis, although no prevertebral soft tissue masses were observed. A total gastrectomy was performed with failure to surgically decompress the ureters because fibrous plaque had firmly enveloped the retroperitoneal structures. biopsy specimens of the retroperitoneum revealed an invasion of the tumor cells and prominent fibrosis. As an etiology of renal failure, ureteral stenosis resulting from secondary retroperitoneal fibrosis was also considered.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |